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1
題名:Studies on the production of some important secondary metabolites from medicinal plants by plant tissue cultures     (44點)
利用組織培養生產藥用植物重要二次代謝物之技術
著者:Chen-Yue Lee(李鎮宇) ;Shu-Fung Lo(羅淑芳) ;Chien Yih Lin(林俊義) ;Hsin-Sheng Tsay(蔡新聲)
出版地區:台灣
出版城市:台北市
學科:生命科學
關鍵字:生物轉換 ; 細胞懸浮培養 ; 毛髮狀根培養 ; 藥學 ; 二次代謝物 ; Biotransformations ; Cell suspension cultures ; Hairy root cultures ; Pharmaceuticals ; Secondary metabolites
刊名:Botanical Bulletin of Academia Sinica
頁碼:1-22
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

藥用植物是新藥開發最重要的資源,目前已有許多對人類健康有益的藥物,是直接由植物的二次代謝物或將此二次代謝物略加修飾之後所獲得,因此,利用組織培養生產植物有用的二次代謝物或提高二次代謝物產能的技術,最近幾十年頗受世界各國學者的重視。始自1960年代末期,三角瓶培養系統以及運用許多不同培養策略的植物細胞培養技術,即被應用於生產二次代謝物之研究。本文綜合報導過去十幾年來組織培養技術應用於藥學領域的研究概況,同時也摘要寫出作者十幾年來從事植物組織培養生產二次代謝物之心得,提供讀者參考。
Plants are a tremendous source for the discovery of new products of medicinal value for drug development. Today several distinct chemicals derived from plants are important drugs currently used in one or more countries in the world. Many of the drugs sold today are simple synthetic modifications or copies of the naturally obtained substances. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in secondary metabolism, particularly in the possibility of altering the production of bioactive plant metabolites by means of tissue culture technology. Plant cell culture technologies were introduced at the end of the 1960's as a possible tool for both studying and producing plant secondary metabolites. Different strategies, using an in vitro system, have been extensively studied to improve the production of plant chemicals. The focus of the present review is the application of tissue culture technology for the production of some important plant pharmaceuticals. Also, we describe the results of in vitro cultures and production of some important secondary metabolites obtained in our laboratory.




本卷期目次
Botanical Bulletin of Academia Sinica
Studies on the production of some important secondary metabolites from medicinal plants by plant tissue cultures/ Chen-Yue LeeShu-Fung LoChien Yih LinHsin-Sheng Tsay
Segregation patterns for integration and expression of Coniothyrium minitans xylanase gene in Arabidopsis thaliana transformants/ Z.-X. LuH. C. Huang
Evolution of apocarpy in Alismatidae using phylogenetic evidence from chloroplast rbcL gene sequence data/ Jin-Ming ChenDan ChenQing-Feng WangYou-Hao Guo
Phosphinothricin tolerance in rice (Oryza sative L.) seedlings is associated with elevated abscisic acid in the leaves/ Yi-Ting HsuChing-Huei Kao
Effect of nitrogen on root and shoot relations and gas exchange in winter wheat/ Z. P. ShangguanM. A. ShaoS. J. RenL. M. ZhangQ. Xue
Effects of Cryptococcus laurentii (Kufferath) Skinner on biocontrol of postharvest decay of arbutus berries/ Xiao-Dong ZhengHong-Yin ZhangYu-Fang Xi
Comparison of Aspergillus flavus and Aspergillus oryzae by amplified fragment length polymorphism/ Chao-Zong LeeGuey-Yuh LiouGwo-Fang Yuan
Ultrastructure of endosperm development in Arundo formosana Hack. (Poaceae) from differentiation to maturity/ Wann-Neng Jane
Notes on the carabidicolous Laboulbeniales (Ascomycetes) of Taiwan I/ Katsuyuki TeradaMeng-Hao HsuWen-Jer Wu
Aster shennongjiaensis (Asteraceae), a new species from central China/ Wei-Ping LiZhi-Guang Zhang
 
   
 
   

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