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1
題名:Postoperative Intensity Modulated Radiation Therapy in Oral Cavity Cancer    
術後強度調控式放射線治療於口腔癌之應用
著者:Shih-Hua Liu(劉士華) ;Yu-Jen Chen(陳裕仁)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:強度調控式放射線治療 ; 口腔癌 ; 手術後放射線治療 ; Oral cavity cancer ; IMRT ; Postoperative radiotherapy
刊名:Journal of the Chinese Oncology Society
頁碼:12-19
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

主題:強度調控式放射線治療於頭頸部癌症的治療已被廣泛的使用。由於強度調控式放射線治療可以提高劑量分布的順形性,使得腫瘤體積內得到充足的放射線劑量並進而減少因放射線治療所引起的毒性反應,所以可達到提高腫瘤控制率和降低正常組織併發症的目的。目前強度調控式放射線治療多應用在沒有切除的頭頸部癌症上;反之,在手術後輔助性治療的運用則較少被探討。口腔癌病患多先接受手術切除,放射線治療的角色則以術後輔助性的型態較多。此篇文章回顧了近年來於口腔癌病患接受術後強度調控式放射線治療的應用,包括治療區域的擬定、劑量的給予、及治療後局部復發的形式,以期能幫助臨床上更多運用。
Intensity-modulated radiation therapy (IMRT) has been widely accepted for treatment of head-and-neck cancers (HNC). The higher conformality of dose distribution produced by IMRT allows tight dose gradients around the target and sharp fall-off near the boundaries. Thus, we can deliver higher dose to the tumor or risky target without increase, or even with decrease, in dose distributed to normal tissues. This may result in improvement of local control as well as reduction of normal tissue damage. However, most published studies of IMRT have focused on treating diseases with gross tumor, resulting in a lack of consensus regarding use of postoperative IMRT for HNC. This unmet need for HNC is of great importance for oral cavity cancers because surgery remains the mainstay treatment. This article reviews the issues in target selection and delineation, dose specification, and the patterns of failure from published reports for postoperative IMRT in oral cavity cancers. We have attempted to provide more and detailed information as a reference for daily practice of treating physicians.




本卷期目次
Journal of the Chinese Oncology Society
Postoperative Intensity Modulated Radiation Therapy in Oral Cavity Cancer/ Shih-Hua LiuYu-Jen Chen
A Good Ending-Holistic Care for Patients with Head and Neck Cancers/ Hong-Wen ChenYu-Jen ChenYi-Shing LeuChung-Ji LiuYi-Fang ChangChun-Kai FangHui-Ching LiuYuen-Liang Lai
Treatment in Patients with Malignant Glial Neoplasms: A Retrospective Analysis of Clinical Parameters, Therapy, and Outcome/ Sheng-Yu ChengCheng-Kuei ChangCheng-Chia Tsai
Clinical Application of 18F-FDG PET and PET/CT in Patients with Head and Neck Cancers/ Bing-Fu ShihChin-Ho TsaoKu-Hung LinMing-Che Wu
Olfactory Groove Meningiomas: Surgical Experience from 35 Cases/ Shu-Mei ChenKuo-Chen WeiShih-Tseng LeeTai-Ngar LuiYung-Hsing HsuTzu-Kang LinChi-Cheng ChuangPeng-Wei HsuChieh-Tsai WuTsung-Che HsiehSai-Cheung LeeChen-Nen Chang
Unusual Presentation of Metastatic Retroperitoneal Lymphadenopathy in Nasopharyngeal Carcinoma/ Yi-Shing LeuChi-Yuan TzenYi-Fang ChangJon-Kway Huang
Ampullary Adenocarcinoma Presenting with Acute Pancreatitis and Anemia/ Hung-Da ChenWen-Hsiung ChangKuo-Shyang JengYu-Jen ChenHuan-Chao LinShou-Chuan ShiYu-Ren Chen
Goblet Cell Carcinoid of the Jejunum/ Shih-Yu HuangWen-Hsiung ChangChien-Liang LiuChi-Kuan ChenShou-Chuan ShihCheng-Hsin Chu
The Successful Closure of Jejunostomy in Sigmoid Colon Cancer with Advanced Intra-Abdominal Carcinomatosis Rescued by Cytoreductive Surgery and Systemic Chemotherapy/ Huan-Chau LinJohnson LinRuey-Kuen HsiehTsang-Pai LiuYi-Fang ChangKa-Ee Ling
以腫瘤出血為表現的中心性腦神經細胞瘤/ 黃亮瑋劉安正黃錚暉林慶揚高木榮張至文白玟娟蕭勝煌
 
   
 
   

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