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1
題名:Metastatic Extra-gonadal Germ Cell Tumor Appearing as a Neck Mass    
以頸部腫塊表現的轉移性生殖細胞癌
著者:Pei-Shih Chen(陳佩詩) ;Yi-Shing Leu(呂宜興) ;Chih-Ming Huang(黃志銘) ;Johnson-Lin(林炯森) ;Yu-Jan Chan(陳瑜珍)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:頸部轉移 ; 絨毛膜癌 ; 性腺外生殖細胞瘤 ; cervical metastasis ; choriocarcinoma ; extragonadal germ cell tumor
刊名:Journal of Cancer Research and Practice
頁碼:28-31
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

性腺外絨毛膜癌好發於年輕之男性,常見的分布位置為身體中線,依機率高低為縱膈腔、松果體區、?尾骨區、後腹膜腔,而肺、肝、骨頭及腦部為其常見轉移部位,轉移至頭頸部並不常見。在所有轉移至頭頸部的原發惡性腫瘤中,最常見的還是頭頸部癌症及惡性淋巴瘤,絨毛膜癌轉移至頭頸部相當罕見,根據文獻報導只有零星幾例病例報告。本科於2008年12月,經歷一位25歲男性因近一個月來腹部疼痛至內科求診無效,安排腹部超音波發現肝門附近多處淋巴結腫大,而後轉介至血液腫瘤科行進一步檢查,理學檢查發現左側頸部淋巴結腫大併頸部腫塊。經由本科進行頸部淋巴結切片術後,β-HCG相當高(H 46508.0 mIU/mL,參考值males:<0-5 mIU/mL),AFP(399.31 ng/mL,參考值<6.00 ng/mL)及LDH(H 1468IU/L,參考值範圍98-192IU/L)確有高於血中正常濃度,確定病理報告為轉移性絨毛膜癌。陰囊超音波檢查並無發現腫塊跡象。病患於2009年一月至七月陸續接受九次化學治療(五次EMA/CO療程,四次BEP療程),現仍持續追蹤中。因為病例罕見,特提出報告。
Extragonadal choriocarcinoma usually presents in the midline of the body, such as the anterior mediastium, pineal gland, sacrococcygeal region and retroperitonium. Extragonadal choriocarcinoma may metastasize to retroperitoneal lymph node, lungs, liver, bone and brain. Metastasis to neck mass is exceedingly rare. We report a rare case of a 25-year-old male who had neck and intra-abdominal masses as the inintial manifestation of extragonadal choriocarcinoma. The patient received five courses chemotherapy of regimen EMA/CO and four courses of BEP. The patient was found with no evidence of disease progression or development of new symptoms in during follow-up.


    

本卷期目次
Journal of Cancer Research and Practice
Surgical Experiences with Intradural Spinal Metastases from Systemic Neoplasms/ Hong-Chieh TsaiHung-Lung ChenYung-Hsing HsuWen-Hsing HsuHsiu-Chuan YenChih-Lung Lin
前哨淋巴結手術在早期乳癌病人的應用與經驗/ 吳思萱余本隆陳啟明楊承恩蔡紫蓉林忠葦程宗彥游冬齡黃玉儀李佩瑛曹美華李明媛莊璦瑛顧文輝林寬仁趙婉純蔡宛蓁楊博勝
Metastatic Extra-gonadal Germ Cell Tumor Appearing as a Neck Mass/ Pei-Shih ChenYi-Shing LeuChih-Ming HuangJohnson-LinYu-Jan Chan
Non-Small-Cell Lung Cancer in Patients Older than Eighty Years/ Kun-Ta ChouYuh-Min ChenKuei-Chih LinChun-Ming TsaiYu-Chin LeeReury-Perng Perng
Choriocarcinoma Presenting as Metastatic Carcinoma of Unknown Primary Origin with Growing Masses at Abdominal Wall/ Hsiang-Fong KaoChih-Hung Hsu
One-Stage Reconstruction of Extensor Mechanism with Free Composite Anterolateral Thigh Flap and Vascularized Fascia Lata after Malignant Tumor Resection of Knee/ Tsung-Sheng NiShih-Hsin ChangTer-Yang HuangHung-Tao HsiaoKwang-Yi Tung
 
   
 
   

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