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題名:Degradation Behavior of Porous Calcium Phosphates     (12點)
多孔鈣磷酸鹽降解行為研究
著者:Chien-Wen Wang(王僅文) ;Min Yan(燕敏) ;Hsien-Chang Chang(張憲彰) ;Shinn-Jyh Ding(丁信智)
出版地區:台灣
出版城市:台南市
學科:醫學綜合
關鍵字:組織工程 ; 多孔骨架 ; 機械性質 ; 鈣磷酸鹽 ; Tissue engineering ; Porous scaffold ; Mechanical property ; Calcium phosphate
刊名:Journal of Medical and Biological Engineering
卷期:23卷3期(2003.9)
頁碼:159-164
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

理想的骨架除了考量材料本身的化性與結構外,需要評估其孔隙率、孔洞大小及機械性質等因素以研究降解性行為。本實驗添加孔原形成劑(PVA),以燒結法製作多孔鈣磷骨架,將此種材料浸泡於Hanks模擬體液中,研究其機械強度變化及重量損失,並觀察微結構形態。結果發現陶瓷骨架表面形成數百微米巨孔與許多微孔的結構,經浸泡於模擬體液後,出現浸蝕引起的微孔。各燒結體抗壓強度隨PVA添加量增加而降低,隨浸泡時間增加各陶瓷骨架之抗壓強度降低,且重量損失增加。本研究的多孔材料或許可使用在骨缺損修補。
Concerning an ideal scaffold, evaluation of many factors, such as porosity, porous size and mechanical properties are needed so as to investigate degradation behavior in addition to chemistry and structure of materials used. In this study, the porous calcium phosphates were made on addition of a pore-former compound (PVA) by sinter processing. Mechanical properties, morphology, and weight change in in vitro testing were assessed. Experimental results indicated macropore sizes as large as hundreds of micrometers were generated and many micropores were also observed in the sintered body. After immersion in Hanks' solution, on the body surface there was a pitting appearance with immersion-induced micropores. The compressive strength of as-sintered bodies decreased steadily with addition of PVA. With increasing immersion time, the compressive strength and modulus of various porous bodies decreased and the weight loss increased. The biomedical uses of the present porous materials might limit to use as bone defect repair.


    

本卷期目次
Journal of Medical and Biological Engineering 23卷3期 (2003.9)
Strain Compounding: Improvement in Contour Extraction of Ultrasonic Breast Imaging/ Wei-Ning LeePai-Chi Li
Structural and Functional Image Registration Using Maximum Mutual Information/ Hsiao-Ling HuangHong-Dun LinBeing-Tau ChungKang-Ping Lin
High Resolution Optical Doppler Tomography for in vivo Blood Flow Dynamics with Pharmacological Intervention/ Cheng-Jen ChangZhong-Ping Chen
Packaging Design for Implantable Microstimulator/ Chi-Chan HungCho-Liang ChungGin-Shu YoungKang-Ping LinJia-Jin Chen
A Web Services Based Brain Tumor Image Exchange System with Single Sign-On Access Management/ Ing-Yi ChenChao-Chi HuangHong-Dun LinKang-Ping Lin
Development of Internet Based Remote Health and Activity Monitoring Systems for the Elders/ Chung-hsien KuoFang-Ghun HuangKeng-Liang WangMing-Yih LeeHuai-Wen Chen
Degradation Behavior of Porous Calcium Phosphates/ Chien-Wen WangMin YanHsien-Chang ChangShinn-Jyh Ding
Quantitative Analysis of 11C-acetate in Nasopharyngeal Carcinoma with Positron Emission Tomography/ Yu-Hua FangTsair KaoLiang-Chih WuRen-Shyan Liu
 
   
 
   

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