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1
題名:Changes in Spinal Motoneuron "Fastness" in Post-stroke Spastic Patients     (12點)
著者:Ling-Yin LiangJia-Jin Jason ChenYu-Lin Wang
出版地區:台灣
出版城市:台南市
學科:醫學綜合
關鍵字:Stroke ; Age-dependence ; Afterhyperpolarization (AHP) ; Human motoneuron (MN) firing patterns ; Neuronal plasticity
刊名:Journal of Medical and Biological Engineering
卷期:30卷1期(2010.2)
頁碼:17-22
語言:英語
摘要: 英文摘要PDF

Motor unit (MU) action potentials trains were recorded from brachial biceps of 11 post-stroke patients (Brunstrom stage 2-4) and 8 healthy volunteers. The variability analysis of interspike intervals (ISIs), aimed at the comparison of the duration of afterhyperpolarization (AHP) in motoneuron (MN), was performed on MUs of 39 controls and 64 patients. Our results concerning MU discharge characteristics conformed in general to the previous reports, showing positive serial correlation coefficients and lower MU firing rates in patients as compared with control subjects. We have found, however, that the positive correlation coefficients result from trends in MU firing rates related to less efficient control of the muscle force. ISI variability determined in short-interval range was the same in patients and control subjects. The transition intervals of variability-mean ISI characteristics, which were previously shown to correlate with AHP duration, were significantly longer in patients, but the prolongation decreased with patient's age and disease duration. Our results indicate that the spinal MNs respond to the cerebral stroke with prolongation of AHP duration, which tends to recover after the accident. These changes are less pronounced in older patients, presumably due to decreased MN plasticity. We conclude that the match between MN and muscle properties is preserved after stroke.


    

本卷期目次
Journal of Medical and Biological Engineering 30卷1期 (2010.2)
Review: Behaviors, Models, and Clinical Applications of Vergence Eye Movements/ Yung-Fu ChenYou-Yun LeeTainsong ChenJohn L. SemmlowTara L. Alvarez
Changes in Spinal Motoneuron "Fastness" in Post-stroke Spastic Patients/ Ling-Yin LiangJia-Jin Jason ChenYu-Lin Wang
IG-GA: A Hybrid Filter/Wrapper Method for Feature Selection of Microarray Data/ Cheng-Huei YangLi-Yeh ChuangCheng-Hong Yang
Extending DNA from a Single Cell using Integrated System of Electro-osmosis and AFM/ Min-Sheng HungPo-Chia Chen
Computer Simulation Based on the Electric Dipole Model: Analysis of the Factors Affecting the Amplitude and the Waveform of the Cat Colon Electrical Control Activity/ Nicola MirizziRoberto MirizziGiuseppe Riezzo
Evaluation of Dose Difference in the Delivered Dose Due to Lung Tumor Motion in Conventional, Conformal and IMRT Treatment Techniques using In-house Developed Dynamic Phantom/ Raghavendiran BoopathyVivekanandan NagarajanDhanabalan RajasekaranSriram PadmanabanPrabakar SukumaranBalakrishnan Irde SankarraoLakshmanan Alathur Venkataraman
Neural Mechanisms of Intuitive Tactical Decision-making Predominance of High-level Fencing Athletes/ Yan FengCheng-Lin ZhouJian-Cheng ZhangMin-Lu Tian
A Virtual Reality Ear Ossicle Surgery Simulator Using Three-dimensional Computer Tomography/ Ming-Shium HsiehFei-Peng LeeMing-Dar Tsai
 
   
 
   

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