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題名:糖尿病視網膜病變和心率變異性之相關研究     (14點)
A STUDY OF RELATIONSHIP BETWEEN DIABETIC RETINOPATHY AND HEART RATE VARIABILITY
著者:郭博昭(B J Kuo(Terry)) ;蔡景耀(Ching-Yao Tsai) ;劉秀雯(Shiow-Wen Liou) ;周碧瑟(Pesus Chou) ;張寅(Yin Chang) ;郭麗琳(Li-Lin Kuo) ;黃麗珊(Li-Shan Huang)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:diabetic retinopathy ; diabetic autonomic neuropathy ; heart rate variability
刊名:中華民國眼科醫學會雜誌
卷期:46卷1期(2007.3)
頁碼:20-26
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

為了暸解是否可由心率動態預測糖尿病患之視網膜病變, 50 位 糖尿病患者參與本研究,依據其視網膜檢查結果將視網膜病變程度分 為四級O 參與者無心臟節律的病變,皆呈現竇房脈O 各組之年齡、性 別分佈、收縮動脈壓和舒張動脈壓並無差異O 每位受試者接受五分鐘 的心電紀錄,並由電腦程式進行非線性與線性分析,前者包括 Correlation Dimension (CD) , Approximate Entropy (ApEn) ,與Largest Lyapunov Exponent (LLE) ,後者包括平均心率週期(RR) 、心率標準差 (SD) 、低頻功率(LF, 0.04-0 .1 5 Hz) 、高頻功率(HF, 0.04-0.15 Hz) ,與低 /高頻功率比值(LF在-1F) 0 相較於第一級無視網膜病變患者,第二級輕 度視網膜病變者所有HRV 分析皆差無顯著差異oRR' LF 和HF 於第 四級重度視網膜病變者顯著下降o ApEn , CD 與LLE 同樣於第四級 顯著下降,然而LLE 在第三級病變組也有顯著變化O 我們認為多種 心率變異性之線性和非線性分析法皆能反應糖尿病患重度視網膜病 變之發生,尤其以非線性之LLE 有最佳之靈敏度O
To explore whether diabetic retinopathy can be predicted by heart rate dynamics, 50 diabetic patients were enrolled in this study. They were c1assified into four groups according to the severity of retinopathy as diagnosed by fundus examination. The four groups did not differ in age, sex distribution, systolic and diasto1ic arterial pressure statistically. The participants had normal sinus rhythms, and five minutes of ECG signals were recorded in daytime while they were Iying quietly. Computer analysis accomplished various linear and nonlinear estimations of heart rate variability (HRV), including mean (RR) and standard deviation (SD) of R-R intervals, low-frequency power (LF, 0.04-0.15 Hz),high frequency power (HF, 0.15-0.4 Hz), LF to HF ratio (LFIHF), correlation dimension (CD), approximate entropy (ApEn), and largest Lyapunov exponent (LLE). Compared with the no retinopathy group (group 1), the mild retinopathy group (group2) did not exhibit evident change in all parameters. However, the severe retinopathy group (group 4) had significantly lower R仗, LF, HF, CD, ApEn, and LLE. It is noteworthy that only LLE altered significantly in the median retinopathy group (group 3). We concluded that severe retinopathy in diabetic patients can be indicated by various linear and non1inear analyses of HRV, in which the nonlinear LLE has the best sensitivity.


    

本卷期目次
中華民國眼科醫學會雜誌 46卷1期 (2007.3)
CLINICAL OUTCOMES OF WAVEFRONT-GUIDED LASER IN SITU KERATOMILEUSIS WITH DIFFERENT MICROKERATOME HEADS FOR THE HIGH MYOPIA--A PRELIMINARY STUDY/ Hui-Chen LinHung-Yu LinWei-hsin LinChin-jung Yeh
2004年台灣地區眼科門診執業內容分析/ 柳逸嫻林宜璁陳曾基周麗芳黃信彰許紋銘
糖尿病視網膜病變和心率變異性之相關研究/ 郭博昭蔡景耀劉秀雯周碧瑟張寅郭麗琳黃麗珊
高度近視患者白內障手術視力預後與相關危險因子之探討/ 張庭嘉郭麗琳劉秀雯翁林仲周碧瑟蔡景耀
LACRIMAL SAC TUMOR--REPORT OF TWO CASES/ Jyun-Ci WangShih-Huag HuangJen-Peng WangYen-Liang ChangSzu-Yuan LinShun-Ling Lin
NASOPHARYNGEAL CARCINOMA WITH INITIAL PRESENTATION OF ISOLATED COMPRESSIVE OPTIC NEUROPATHY--A CASE REPORT/ Pei-Chen ChangMay-Yung YenYen-Ching LinAn-Guor Wang
OCULAR THELAZIASIS MANIFESTED AS CONJUNCTIVITIS--A CASE REPORT/ Pei-Jen ChenShih-Chen ChenShu-Wen Chang
TOPICAL CYCLOSPORINE A 0.05% IN THE TREATMENT OF SUPERIOR LIMBIC KERATOCONJUNCTIVITIS/ Sheng-Fu ChengChi-Hsien PengCheng-Kuo Cheng
BILATERAL VITREOUS HEMORRHAGE: AN UNUSUAL PRESENTATION OF PRESUMED OCULAR SARCOIDOSIS--CASE REPORT/ Chia-Shian LinShwu-Jiuan Sheu
ORBITAL APEX SYNDROME AND CENTRAL RETINAL ARTERY OCCLUSION CAUSED BY MUCORMYCOSIS--CASE REPORT/ Yu-Lun LoChao-Chien Hu
INTRAOPERATIVE CAPSULAR BLOCK SYNDROME: A CASE REPORT/ Jia-Kang Wang
MUCOEPIDERMOID CARCINOMA OF THE LACRIMAL GLAND: A CASE REPORT AND LITERATURE REVIEW/ I-hua WangGing-Shan HuangShin-Hung HuangSzu-Yuan LinShun-Ling Lin
MANAGEMENT OF AN ANTERIORLY DISLOCATED CRYSTALLINE LENS AND ACUTE SECONDARY ANGLE-CLOSURE GLAUCOMA BY ENDOCAPSULAR PHACOEMULSIFICATION IN THE ANTERIOR CHAMBER AND IRIS-FIXATED INTRAOCULAR LENS IMPLANTATION: A CASE REPORT/ Andy Y LoJia-Kang WangPei-Jen ChenChao-Yu Hu
PNEUMATIC RETINOPEXY FOR RHEGMATOGENOUS RETINAL DETACHMENT/ Ching-Yao TsaiTing-Jia ChangPesus ChouShiow-Wen Liou
SUPRACHOROIDAL HEMORRHAGE--A CASE REPORT/ Chia-Min TsaiTai-Yuen Wang
PRIMARY LYMPHOMA OF THE LACRIMAL SAC--A CASE REPORT/ Hsin-Hui WangShu-Ching KaoChieh-Chih TsaiShyh-Haw TsayWen-Ming Hsu
角膜移植手術中併發膨出性上脈絡膜出血--病例報告/ 劉美麟陳俊寰魏福宗陳伯卿林主國蔡武甫
 
   
 
   

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