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題名:CORNEAL INTRAEPITHELIAL NEOPLASIA     (16點)
角膜上皮贅瘤
著者:Liang-Jung Su(蘇良榮) ;Ray-Fong Lee(李瑞鋒) ;Shew-Gin Yow(游琇瑾) ;Po-Chiung Fang(方博炯) ;Wei-Chi Chang(張維基)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:Corneal intraepithelial neoplasia ; dysplasia ; corneal topographic change ; human papillomavirus
刊名:中華民國眼科醫學會雜誌
卷期:38卷3期(1999.9)
頁碼:328-335
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

目的:研究角膜上皮贅瘤在臨床上及病理上的特徵。 方法:我們提出八位角膜上皮贅瘤病例。這些病例都做角膜地圖儀檢查、手術切除及病理檢查。 結果:角膜地圖儀顯示出與混濁相關的散光。在病理上,它表現出上皮細胞過度增生、細胞排列極性消失及形狀不規則的特色。其中五例表現陽性human papillomavirus反應,兩例有細胞核皺縮及細胞內空泡現象,一例有細胞分裂變化。切除角膜混濁後,大部份病人有明顯的視力改善,在追?期間僅有一例有復發情形。 結論:我們認?角膜上皮贅瘤可能與human papillomavirus有密切關聯,且是個癌症前期變化。它會造成角膜的散光。手術切除可消除病灶及迅速恢復視力,但需小心長期追?。
Purpose: To study the clinical and pathologic characteristics of corneal intraepithelial neoplasia. Methods: Eight corneal intraepithelial neoplasia cases were presented in this study. Keratometry, topography, surgical debridement, and pathologic examination were performed for these cases. Results: Topography revealed astigmatism associated with the epithelial opacity. Pathologically, corneal intraepithelial neoplasia was characterized by hyperplasia of the epithelial cellular layer, loss of cellular polarity, and irregular cellular shape. Five cases revealed positive reaction in human papillomavirus immunohistochemistry study, two cases showed koilocytosis, and one case showed mitotic change. After removal of the membranous corneal opacity, most cases had great visual improvement. One recurrence was noted during the follow-up period. Conclusions: We find that corneal intraepithelial neoplasia may be associated with human papillomavirus, and may present as a precancerous change. It results in flattened effect corneal astigmatism. Although surgical management can eliminate the lesion and improve the vision promptly, all corneal intraepithelial neoplasia patients need long-term careful follow-up.


    

本卷期目次
中華民國眼科醫學會雜誌 38卷3期 (1999.9)
A REVIEW OF MYOPIA STUDIES IN TAIWAN/ Shirley Hsiao-Ching ChangYung-Feng ShihLuke L-K. Lin
CORNEAL INTRAEPITHELIAL NEOPLASIA/ Liang-Jung SuRay-Fong LeeShew-Gin YowPo-Chiung FangWei-Chi Chang
CORNEAL ENDOTHELIAL CHANGES FOLLOWING LONG-TERM GLAUCOMA FILTERING OPERATION/ Sung-Huei TsengFred. K. Chen
EFFECT OF LOWER LID TRACTION SUTURE--PREVENTION OF LOWERLID RETRACTION ASSOCIATED WITH INFERIOR RECTUS MUSCLE RECESSION SURGERY/ Brian Bing-Herng ShenMin-Hui Wu
THE OUTCOMES OF TRABECULECTOMY WITH OR WITHOUT MITOMYCIN IN ICE SYNDROME/ Chun-His LiuWan-Chen Ku
以雷射都卜勒視網膜血流計分析糖尿病性視網膜病變/ 林偉常黃正賢李原傑黃兆康陳慕師洪伯廷
糖尿病增殖性視網膜病變接受玻璃體切除鞏膜扣箍及二極體泛視網膜光凝固術產生脈絡膜剝離或滲出性視網膜剝離/ 林偉欣鄭成國盧雪玉
嬰兒搖晃症候群視力預後之評估/ 黃瓊瑢林慧茹蔡三章沈戊忠
早產兒的視覺發育和屈光狀態/ 吳愛卿藍郁文
晶體前表面弧度與閉鎖性青光眼的關係/ 江靜弘郭翰欽翁林仲
鼻腔內視鏡之減壓手術治療甲狀腺相關之眼窩病變/ 林睦秋林耀溢周俐禎楊宜璋洪熒燦朱繡棟
準分子雷射屈光性角膜切除術術後之角膜彩色地圖分析:在嘉義基督教醫院的經驗/ 林純如譚超毅蔡忠斌張國彬羅崇源林文燕
眼科常用之三種散瞳劑對學童眼壓之影響/ 徐加容游建章曾國亮
A SUCCESSFUL TREATMENT OF NEUROTROPHIC ULCER WITH AMNIOTIC MEMBRANE TRANSPLANTATION/ Chia-Yun LiSamuel C M HuangHui-Chun LaiRay Jui-Fang Tsai
NEUROBLASTOMA METASTATIC TO THE BONY ORBIT--A CASE REPORT/ Hon-Chun ChengYi-Sheng ChangJiann-Shiuh Chen
虹膜裂-兩例報告及臨床回顧/ 林蓓雯賴盈州鄧美琴蔡振嘉
 
   
 
   

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