原名「台灣學術線上」
包含TAO期刊庫 + TAO書籍庫 + 論文 + 史料文獻
首頁 | 關於TAO | 瀏覽 | 進階查詢 | 參考工具 | 會員服務 | 已購專書 | RSS服務 | 電子報 | FAQ  
查詢範圍:
   
查詢模式:
熱門查詢詞:
dvdDiy扣件原住民教育困境OTA
   
   
   
     
   
 
項次 書目
1
題名:PREOPERATIVE RADIOTHERAPY AND CHEMOTHERAPY FOR LOW OR LOCALLY ADVANCED RECTAL CANCER     (20點)
手術前放射合併化學治療對低位或局部侵犯厲害直腸癌之治療成果
著者:I-Chun Yeh(葉怡君) ;Helen H. W. Chen(陳海雯) ;Jeng-Chang Lee(李政昌) ;Wu-Chou Su(蘇五洲) ;Hong-Ming Tsai(蔡宏名) ;Henry W. C. Leung(梁永昌)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:直腸癌 ; 手術前放射治療 ; 括約肌保存 ; Rectal cancer ; Preoperative radiotherapy ; Sphincter preservation
刊名:Therapeutic Radiology and Oncology
頁碼:27-36
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

且且:對低位或局部侵犯厲害直腸癌的病人以于術前放射合併化學治療的方式,評估其肛門括約肌保存率及降低疾病分期之治療成果。 材料與芳注:從1 9 9 9 年到200 1 年, 共有1 5 位直腸癌的病人( 13 位男性、2 位女性) 在本院接受于術前放射合併化學治療的方式。其中三位患有局部侵犯厲害直腸癌,另外1 2位則患有腫瘤距離肛門括約肌6公分以內的低位直腸癌。病人年紀分佈範圍自27到73歲不等。依據治療前電腦斷層檢查及肛門觸診作為臨床分期的標準,則計有2位AJCC分期T2NO、10位T3NO、1 位T3Nl 、2 位T4NO 的病人。這些病人均接受每日分次劑量1.8 Gy ,骨盆腔總劑量的Gy的傳統多照野放射線治療,同時台併以5 - FU為主的化學治療,並在放射治療及化學治療完成後6到8週接受手術。 益墨:有1 0位病人( 679毛) 經手術後病理報告證實腫瘤疾病分期確有降低, 其中包括3 位腫瘤完全消失、l位TI NO、4位T2NO '和2 位T3 NO 的病人。在1 2 位低位宜腸癌的病人中有8位( 6 7 % )可以達到肛門括約肌保存的目的。1 5位病人的術式分別為:直腸切除及大腸肛門吻合術( 7位)、低前位切除術( 4位)、經腹部會陰切除術( 4位)。治療過程中並沒有發生嚴重治療副作用的情形;同時,到目前為止存活的病人中均沒有疾病局部復發。 益益:手術前放射合併化學治療的方式對低位或局部侵犯厲害直腸癌的病人有6 7%可以得到降低腫瘤分期的效果,在低位直腸癌的病人有6 7%亦可以達到肛門括約肌保存的目的,同時病人有很好的耐受性,臨床上是一個可行的方式。
Purpose: To evaluate the rates of tumor down-staging and sphincter-sparing surgery for low or locally advanced rectal cancers after preoperative radiotherapy and chemotherapy. Methods and Materials: During the period between 1999 and 2001, 15 patients (13 males and 2 females) received preoperative radiotherapy and chemotherapy followed by surgery for localized adenocarcinoma of the rectum. Three of them had locally advanced unresectable rectal cancer and 12 patients had lOW-lying rectal cancer (within 6 em from the anal verge). Patients' age ranged from 27 to 73 years (median, 48). Pretreatment tumor stages, determined by the CT scan, included 2 with T2NO, 10 with T3NO, 1 with T3N1, and 2 with T4NO. The preoperative treatment procedure consisted of conventionally fractionated irradiation of 45 Gy in 25 fractions to the pelvis with concomitant 5FUbased chemotherapy 6-8 weeks before surgery. Results: Tumor down-staging was pathologically confirmed in 10 (67%) of 15 patients, including 3 with complete response (CR), 1 T1NO, 4 T2NO, and 2 T3NO disease. Sphincter preservation was accomplished in 8 (67%) of 12 low rectal cancer patients. The surgical procedures included proctectomy and coloanal anastomosis (n = 7), low anterior resection (n =4), and abdominoperineal resection (n =4). All patients tolerated the combined chemoradiotherapy approach well without grade 3 or 4 toxicity. There was no pelvic disease recurrence till now. Conclusion: The combination of preoperative pelvic radiation and 5-FU infusional chemotherapy in the management of low or locally advanced rectal cancers was well tolerated. Preoperative chemoradiotherapy resulted in significant tumor down-staging, allowing sphincter-sparing surgery in 67% of patients whose tumors were located within 6 em from the anal verge and who otherwise would have required a colostomy.


    

本卷期目次
Therapeutic Radiology and Oncology
Definitive Radiotherapy for the Patients with Prostatic Adenocarcinoma: Analysis of Short-Term Outcome and Prognostic Factors/ Shena Yu-Hsuan ChenJason Chia-Hsien ChengStella Y. TsaiSkye Hon-Giun ChengDaniel S. ChangAlex Lien-Yen YangJames Jer-Min Jian
Preperative Radiotherapy Concurrent with Chemotherpy for Locally Advaced Rectal Cancer/ Yu-Xuan ChenWilliamChenMu-Tai LiuChih-Yuang ChungCheng-Shyong ChangGer-Hau HsuHong-Chang ChenTung-Hao ChangChu-Ping PiChih-Chiech Hsu
雙盲對照實驗評估口服pilocarpine對放射線治療引起頭頸部癌症病患口乾症於馬偕醫院之使用主觀效果及安全性報告/ 陳舜鼎張國華陳裕仁鍾昌宏吳孟浩蘇文浩陳虹汶賴允亮
改良式軟片劑量驗證應用於強度調控放射線治療之先期研究/ 蔡忠宏莊克士戴宏旗周志成蕭安成林芳仁
固定深度治療對直腸肛門癌放射治療的影響/ 曾雁明范綱行白冰清蔡介生林倩伃陳臣苑曾振淦
AAPMTG-51號議定書光子與電子劑量計算程式/ 郭力誠鄭秀成游浚彥陳妙芬陳文政
Preoperative Radiotherapy and Chemotherapy for Low or Locally Advaced Rectal Cancer/ I-Chun YehHelen H.W. ChenJeng-Chang LeeWu-Chou SuHong-Ming TsaiHenry W.C. Leung
DEFINITIVE RADIOTHERAPY FOR THE PATIENTS WITH PROSTATIC ADENOCARCINOMA: ANALYSIS OF SHORT-TERM OUTCOME AND PROGNOSTIC FACTORS/ Shena Yu-Hsuan ChenJason Chia-Hsien ChengStella Y TsaiSkye Hongiun ChengDaniel S ChangAlex Lien-Yen YangJames Jer-Min Jian
雙盲對照實驗評估口服pilocarpine對放射線治療引起頭頸部癌症病患口乾症於馬偕醫院之使用主觀效果及安全性報告/ 陳舜鼎張國華陳裕仁鍾昌宏吳孟浩蘇文浩陳虹汶賴允亮
PREOPERATIVE RADIOTHERAPY CONCURRENT WITH CHEMOTHERAPY FOR LOCALLY ADVANCED RECTAL CANCER/ Yu-Xuan ChenWilliam ChenMu-Tai LiuChih-Yuang ChungCheng-Shyong ChangGer-Hau HsuHong-Chang ChenTung-Hao ChangChu-Ping PiChih-Chiech Hsu
PREOPERATIVE RADIOTHERAPY AND CHEMOTHERAPY FOR LOW OR LOCALLY ADVANCED RECTAL CANCER/ I-Chun YehHelen H. W. ChenJeng-Chang LeeWu-Chou SuHong-Ming TsaiHenry W. C. Leung
固定深度治療對直腸肛門癌放射治療的影響/ 曾雁明范綱行白冰清蔡介生林倩?陳臣苑曾振淦
AAPMTG-51號議定書光子與電子劑量計算程式/ 郭力誠鄭秀成游浚彥陳妙芬陳文政
改良式軟片劑量驗證應用於強度調控放射線治療之先期研究/ 蔡忠宏莊克士戴宏旗周志成蕭安成林芳仁
 
   
 
   

與TAO合作 | 隱私與版權聲明 | 聯絡方式 | 下載Adobe Reader
地址:台北市中正區(100)北平東路30-12號3樓
電話:(02)2393-6968 傳真:(02)2393-6877
Email: service@wordpedia.com
Wordpedia Family: 學校、企業版入口 | 遠流影音館
Copyright©2011 Wordpedia Co., Ltd. All Rights Reserved.