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dvdDiy扣件原住民教育困境OTA
   
   
   
     
   
 
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題名:婦癌病人一天照射兩次之文獻回顧及個人經驗     (8點)
Hyperfractionation Radiotherapy in the Gynecological Cancers Literature Review and Personal Experience
著者:詹建勝(Jian-Sheng Jan) ;張慶雄(Ching-Shysiong Chang) ;林進清(Jin-Ching Lin) ;翁益強(Yih-Chyang Weng) ;高忠恕(Jong-Shuh Gau)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
刊名:放射治療與腫瘤學
頁碼:43-46
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

一天照射兩次之放射線治療技術,對較晚期之頭頸部癌,已有許多文獻報告,可以增加局部之 腫瘤控制率,而已廣氾地被使用。但運用在婦科腫瘤如子宮癌則很少,本院於8 1年會以此方法治療 兩個病例,一例為復發性子宮頸癌,一例為l i B期子宮頸癌,均以一天照射兩次每次問隔6小時以上, 早上照射前後照野1 . 8葛雷,下午照射兩側照野1 . 2葛雷,共照射1 5天, 45 葛雷, 然f是改用一般治 療方法,第二例有3日3天之ci s p l a t i n作為放射敏感劑,兩例之腫瘤控制都很好,已維持1 7個月,但兩 例均有較明顯之急性反應包括腹J寫,裡急後童,自血球降低等,需休息一至二週。文獻報告方面, 只有兩篇用此技術治療子宮頸癌,結果腫瘤控制並沒有比一般治療方法增加,而急性反應則有很明 顯的增加。由於用一天照射兩次之技術應用在婦癌方面可能增加一些急性副作用,而腫瘤控制率並 沒有明顯增加,故很少使用。
That the radiotherapy with hyperfractionation technique can improve the local tumor control rate has been reported in lots of literature in therapy for advanced head and neck cancers and other cancers but little in gynecological cancers. In 1992we treated 2 cases with carcinoma of the uterine cervix by two fractions per day. Case I had recurrent tumor in the vaginal cuff and case II had FIGO stage lIB disease. Both cases received hyperfractionation with 1.8 Gy from AP and PA portals in the morning and 1.2 Gy from bilateral opposing portals in the afternoon at interval of at least 6 hours. We delivered up to 45 Gy in 15days, rested for 1-2 weeks, and then changed the dose as in the conventional radiotherapy with 2 Gy per day. Case I totally received 72.6 Gy in 43 fractions in 59 days. Case II received 65 Gy in 40 fractions in 45 days. Case II also received concomitant chemotherapy with 30 mg cisplatin for 3 days in the second week of radiotherapy as a radiation sensitizer and intracavitary brachytherapy to the uterine cavity with 500cGy to point A for each treatment and totally for 5 treatments after external radiotherapy. After radiotherapy both cases developed moderate to severe acute reactions including diarrhea, tenesmus and low white count in 2 weeks of the hyperfractionation treatment. But the acute reactions were soon recovered after a rest of 1-2 weeks. In our follow-up as of July 1993, there was no late complication and the case were with good local controland without distant metastasis up to 17 months.The literature, review demonstrated only 2 reports regarding hyperfractionation of the gynecological cancershad been reported. The local tumor control in is 2 reports did not show any significant improvement and the increased acute normal tissue reactions showed in one report. In conclusion, hyperfractionation technique for gynecological cancers may induce more acute reactions but may not increase the local control rate, so,it is not frequently applied in the therapy for gynecological cancers.


    

本卷期目次
放射治療與腫瘤學
惡性腦部星細胞瘤的放射治療近況/ 許文林
利用線性二次元模式及其相關公式估算一日多次放射治療或改變每次照射劑量時之等效劑量/ 林忠毅吳永平
Hyperfractionation for Head & Neck Cancer: a Preliminary Report From Chang-Hua Christian Hospital/ Mu-Tai Liu
一日多次放射治療不同方法之比較/ 梁永昌郭珍妮王美淑郭永芳
每日兩次治療鼻咽癌的經驗/ 黃淑珍
多分次照射與重複照射對脊髓放射線耐受力之影響:幾篇文獻之閱讀報告/ 任益民
線性二次方(LQ)模式、分次敏感度、α/β、與相對效應/ 任益民
肺癌病人一日照射兩次之文獻回顧/ 胡渝昌吳永平
Radiotherapy of Nasopharyngeal Carcinoma in the Young Age Group: a Review From Mackay Memorial Hospital/ Chung-Yu KaoYuen-Liang LaiChang-Hung ChungChi-Yuan YehMeng-Hao WuKuo-Hwa Chang
總治療時間在放射治療不同方法比較上的重要性/ 季匡茟陳光耀
多形性神經膠母細胞瘤一日多次加速度照射之文獻回顧及個人經驗/ 陳惠君梁雲王重榮
不完全修復在一天多次照射時之重要性/ 丁禮莉
A Dose Response Analysis For Cytotxic Drugs (Ⅰ) Alpha,Beta,Gamma Model/ Kwan-Hwa ChiJack.F.FowlerKuang-Y ChenTimothy J.Kinsella
線性二次方(LQ)模式之臨床運用與不完全修復的重要/ 任益民
婦癌病人一天照射兩次之文獻回顧及個人經驗/ 詹建勝張慶雄林進清翁益強高忠恕
頭頸部腫瘤放射治療分次方式改變之臨床結果-文獻回顧/ 蘇志中
A Dose Response Analysis for Cytotxic Drugs (Ⅰ) Alpha, Beta, Gamma Model/ Kwan Hwa ChiKuang Y. Chen
多形性神經膠母細胞瘤一日多次加速度照射之文獻回顧及個人經驗/ 陳惠君梁雲王重榮
Radiotherapy of Nasopharyngeal Carcinoma in the Young Age Group: A Review from Mackay Memorial Hospital/ Chung-Yu KaoYuen-Liang LaiChang-Hung ChungChi-Yuan YehMeng-Hao WuKuo-Hwa Chang
惡性腦部星細胞瘤的放射治療近況/ 許文林
Hyperfractionation for Head & Neck Cancer: A Preliminary Report from Chang-Hua Christian Hospital/ Mu-Tai Liu
每日兩次治療鼻咽癌的經驗/ 黃淑珍
婦癌病人一天照射兩次之文獻回顧及個人經驗/ 詹建勝張慶雄林進清翁益強高忠恕
線性二次方(LQ)模式、分次敏感度、α/β、與相對效應/ 任益民
線性二次方(LQ)模式之臨床運用與不完全修復的重要/ 任益民
不完全修復在一天多次照射時之重要性/ 丁禮莉
總治療時間在放射治療不同方法比較上的重要性/ 季匡華陳光耀
利用線性二次元模式及其相關公式估算一日多次放射治療或改變每次照射劑量時之等效劑量/ 林忠毅吳永平
一日多次放射治療不同方法之比較/ 梁永昌郭珍妮王美淑郭永芳
多分次照射與重複照射對脊髓放射線耐受力之影響:幾篇文獻之閱讀報告/ 任益民
頭頸部腫瘤放射治療分次方式改變之臨床結果-文獻回顧/ 蘇志中
肺癌病人一日照射兩次之文獻回顧/ 胡渝昌吳永平
 
   
 
   

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