原名「台灣學術線上」
包含TAO期刊庫 + TAO書籍庫 + 論文 + 史料文獻
首頁 | 關於TAO | 瀏覽 | 進階查詢 | 參考工具 | 會員服務 | 已購專書 | RSS服務 | 電子報 | FAQ  
查詢範圍:
   
查詢模式:
熱門查詢詞:
   
   
   
     
   
 
項次 書目
1
題名:BILE DUCT CANCER, ITS SURVIVAL AND LOCAL-CONTROL AFTER RADIOTHERAPY     (16點)
膽道癌放射線治療後之存活率以及局部控制
著者:Fu-Ti Chang(張富迪) ;Ngan-Ming Tsang(曾雁明) ;You-Kang Chang(常佑康) ;Wai-Man Leung(梁為民)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:膽道癌 ; 放射線治療 ; 預後因子 ; 存活 ; Bile duct cancer ; Radiotherapy ; Prognostic factor ; Survival
刊名:Therapeutic Radiology and Oncology
頁碼:133-140
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

旦且: 此篇報告提供了本院過去1 7 年來的膽道瘟病患放射線治療結果的回溯性分析。此研究乃是根據他們的臨床症狀報告、手術中發現以及放射線治療給予的方法等去分析存活率以及局部控制率。 材料與貴注: 自西元1 9 8 5 年至20 03 年, 長庚醫院放射腫瘤科共有2 2 8 位轉診的膽道癌病患。在此研究中,我們只選擇其中7 8位沒有遠處器官轉移、並且接受了膽道系統局部病仕治療的病患來加以分析。其中5位病患只接受了腔內放射線治療(I LRT ) ' 15 位同時接受了體外放射線治療( EB RT )和腔內放射線治療,而5 8位病患只接受了體外放射線治療。此研究分析了影響存活率和局部控制率的預後因子。這些因子包括他們的臨床症狀徵象(黃痘及疼痛) 、過去有無肝膽疾病病史、活動能力( pe rforman ce status ' 即Karn o fs ky sc ale ) 、手術中的發現( 如淋巴腺體, 神經周圍、以及門靜脈有無侵犯) 、組織病理報告、C EA f直以及放射線治療方法與劑量等。 誼星: 追蹤期從l 個月到1 60 個月不等( 中位數17 個月) 。這78 個病息放射線治療後的五年存活率為1 1.3 % ' 而存活中位數為7 個月( 9 5 % 信賴區間為4.4 到9 . 9 個月) 。對存活率有負面影響的因素包括: 神經周邊和淋巴腺體的侵犯、較差的活動能力、伴有疼痛以及黃痘、組織學細胞分化不良、單一方法的放射線治療、以及較低的放射線劑量等。而影響局部控制率最主要的因素為手術後、放射線治療前,有無殘存的膽道癌病仕。 益益: 對於膽道癌病患, 建議較高的放射線劑量以得到較好的存活率。而單獨給予腔內放射線治療的效果仍有爭議。既然手術後有無殘存的膽道癌病仕對於局部控制相當關鍵,手術若能完全將腫瘤切除是必要的;若能早期診斷膽道癌, 也將能達到更好的治療效果。
Purpose : This report retrospectively reviewed bile duct cancer cases at the authors’ institution over the past 17 years. Statistical methods have been employed to analyze overall survival and local-control rates of these cases, and to identify the correlations between different panameters such as the presenting symptoms and signs, surgical findings, radiotherapy (RT) dose, and the RT modality. Materials and Methods : Between 1985 and 2003, the Department of Radiation Oncology at the Chang Gung Memorial Hospital, Linkou, had 228 patients with bile duct cancer referred for RT. Only the 78 patients with no distant organ metastases who underwent treatment for localized biliary system lesions were included in this study. Five patients received intra-luminal RT (ILRT) alone, 15 had external beam RT (EBRT) plus ILRT, and 58 patients received EBRT alone. Statistical methods were employed to identify factors that affected overall survival and local-control rates. These factors include patients’ presenting symptoms and signs (jaundice and pain), a past history of hepatobiliary disease, pre-operative performance status (Karnofsky score), surgical findings (lymph node, perineural, and portal vein involvement), histological and pathological classification, CEA level, the radiation modality and the radiation dose. Results : The follow-up periods ranged from 1-160 months (median 17 months). The 78 patients had a 5-year overall survival rate of 11.3% after RT, and the median survival was 7.0 months (95% CI, 4.4- 9.9 months). Peri-neural and lymph node involvement, poor performance status, presence of pain and/ or jaundice, poorly differentiated histology, single RT modality and lower radiation doses were factors that correlated negatively with survival. The local control rate was most significantly affected by the presence of residual disease prior to RT. Conclusion : Higher doses RT offers a better survival to patients with bile duct cancers. The benefit of ILRT given alone remains unclear. Since residual disease appears to be critical for local control, complete resection of the tumor is essential; which reinforces the importance of early diagnosis of bile duct cancer.


    

本卷期目次
Therapeutic Radiology and Oncology
Treatment Results of Langerhans Cell Histiocytosis: A Long Term Follow-Up/ Chun-Shu LinJing-Min HwangYee-Min JenYi-Jen PengLi-Ping ChangHsing-Lung ChaoDai-Wei LiuHon-Yi LinWeng-Yoon Shum
癌症患者放射治療後迴診追蹤中斷的原因及分析/ 林奎利郭珍妮林立青林逢嘉蘇玫綺
An Evaluation of the Contents and Quality of Radiation Oncology Homepages in Taiwan/ Yu-Jie HuangChong-Jong WangChang-Yu WangChing-Hui HsiehShiao-Hen Chang
預防動靜脈瘻管阻塞之狹長型電子射束劑量分析/ 柯卉玲許淑惠蕭安成李俊信林芳仁季匡華
Bile Duct Cancer, Its Survival and Local-Control after Radiotherapy/ Fu-Ti ChangNgan-Ming TsangYou-Kang ChangWai-Man Leung
頭頸部放射治療的活體劑量驗證/ 王慧娟羅素花董傳中吳嘉明王重榮
Metaplastic Carcinoma of the Breast: One Case Report and Literature Review/ Daniel WinardiShi-Long LianChih-Jen HuangKun-Bow TsaiJui-Sheng HsuMing-Feng Hou
Granulocytic Sarcoma of the Uterine Cervix: A Case Report and Review of the Literature / Ming-Yii HuangShi-Long LianChih-Jen HuangSheng-Fung LinKun-Bow TsaiCheng-Hui Yang
BILE DUCT CANCER, ITS SURVIVAL AND LOCAL-CONTROL AFTER RADIOTHERAPY/ Fu-Ti ChangNgan-Ming TsangYou-Kang ChangWai-Man Leung
AN EVALUATION OF THE CONTENTS AND QUALITY OF RADIATION ONCOLOGY HOMEPAGES IN TAIWAN/ Yu-Jie HuangChong-Jong WangChang-Yu WangChing-Hui HsiehShiao-Hen Chang
癌症患者放射治療後迴診追蹤中斷的原因及分析/ 林奎利郭珍妮林立青林逢嘉蘇玫綺
預防動靜脈?管阻塞之狹長型電子射束劑量分析/ 柯卉玲許淑惠蕭安成李俊信林芳仁季匡華
頭頸部放射治療的活體劑量驗證/ 王慧娟羅素花董傳中吳嘉明王重榮陳惠君
TREATMENT RESULTS OF LANGERHANS CELL HISTIOCYTOSIS: A LONG TERM FOLLOW-UP/ Chun-Shu LinJing-Min HwangYee-Min JenYi-Jen PengLi-Ping ChangHsing-Lung ChaoDai-Wei LiuHon-Yi LinWeng-Yoon Shum
GRANULOCYTIC SARCOMA OF THE UTERINE CERVIX: A CASE REPORT AND REVIEW OF THE LITERATURE/ Ming-Yii HuangShi-Long LianChih-Jen HuangSheng-Fung LinKun-Bow TsaiCheng-Hui Yang
METAPLASTIC CARCINOMA OF THE BREAST: ONE CASE REPORT AND LITERATURE REVIEW/ Daniel WinardiShi-Long LianChih-Jen HuangKun-Bow TsaiJui-Sheng HsuMing-Feng Hou
 
   
 
   

與TAO合作 | 隱私與版權聲明 | 聯絡方式 | 下載Adobe Reader
地址:台北市中正區(100)北平東路30-12號3樓
電話:(02)2393-6968 傳真:(02)2393-6877
Email: service@wordpedia.com
Wordpedia Family: 學校、企業版入口 | 遠流影音館
Copyright©2011 Wordpedia Co., Ltd. All Rights Reserved.