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題名:RADIOTHERAPY FOR SQUAMOUS CELL CARCINOMA OF THE MAXILLARY SINUS     (14點)
上頷竇之鱗狀上皮細胞癌放射治療結果分析
著者:Y. C. Jeffrey Chao(趙勇全) ;Jian-Sheng Jan(詹建勝) ;Jin-Ching Lin(林進清)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:上頷竇 ; 鱗狀上皮細胞癌 ; 放射治療 ; Maxillary sinus ; Squamous cell carcinoma ; Radiotherapy
刊名:Therapeutic Radiology and Oncology
頁碼:39-45
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

且且:在所有頭頸癌中,源自上頭竇的惡性腫瘤相對較罕見。本回溯性研究的目的是,分析一個醫學中心32 例接受根治性放射治療之上頡竇鱗狀上皮細胞癌的治療結果。 材料血?可注:病歷、放射治療資料、以及電腦斷層攝影均經{再回分析。其中男性2有4 人,女性8 人0 年齡分布從33 到76 歲,中位數63 歲。大部分病人(84 .4% )診斷時已屬局部嚴重侵犯(T4 )。治療的方式有于術合併術後放射治療(20 例)、放射治療合併(7例)或不合併(5 例)化學治療。放射治療劑量範圍從50-90 Gy ,中位數為70Gy ,大多以傳統分次方式治療。 結果:五年局部控制率為57.0% '五年總存活率及無病存活率分別為12.5% 及40.7% "其中有13 位病人(40.6% )腫瘤復發或遠處遠移,包括8 例局部復發、I 例頸部轉移、1 例遠處遠移、1 例局部復發合併遠處轉移、以及2 例局部復發合併頸部及遠處轉移。Kaplan-Meier 存活曲線分析顯示:年齡是無病存活率(P =0.018) 及總存活率(P =0.059) 最重要的預後因素。 益益:我們的資料顯示,治療失敗處以局部復發最常見,除了適當的手術切除,未來加強放射治療效果的方式(三度空間順形或強度調控放射治療、改變分次放射治療)、以及同步化學治療等值得進一步研究。
Purpose : Malignant tumors arising from the maxillary sinus are relatively rare among head and neck cancer. The aim of this retrospective study is to analyze clinical outcome of 32 patients with squamous cell carcinoma of maxillary sinus treated by curative intent in a medical center. Materials and Methods : Chart, radiotherapy data, and CT scan were reviewed in detail. There were 24 males and 8 females. Their age ranged from 33 to 76 (median 63) years old. Most patients (84.4%) presented with T4 disease. Treatment modalities were radical surgery + postoperative radiotherapy (20 cases), radiotherapy with (7 cases) or without (5 cases) chemotherapy. The range of radiation dose was 50-90 Gy with a median of 70 Gy by conventional fractionation. Results : The estimated local control rate at 5 years was 57.0%. The 5-year overall and disease-free survival rates were 12.5% and 40.7% respectively. Thirteen of 32 (40.6%) patients developed tumor recurrence or metastasis. The failure pattern illustrated 8 local recurrences, 1 neck metastasis, 1 distant metastasis, 1 local recurrence with distant metastasis, and 2 local recurrences with neck and distant metastasis. Kaplan-Meier survival analyses and log-rank test showed that age was the most important prognostic factor affecting disease-free survival (P = 0.018) and overall survival (P = 0.059). Conclusion : Our data suggest that primary recurrence is the major site of failure. Except for adequate surgical resection, approaches that can enhance radiation effect (3- D conformal or intensity-modulated radiotherapy and altered fractionated radiotherapy) and concurrent chemotherapy deserve to be tried in the future.


    

本卷期目次
Therapeutic Radiology and Oncology
Surgery Followed by Concurrent Chemoradiation with Weekly Cisplatin and Adjuvant Systemic Chemotherapy for Locally Advanced Esophageal Cancer-A Pilot Study/ Kuo-Hwa ChangShih-Kai HungHung-Chang LiuCharng-Jer HuangYuen-Liang LaiYu-Jen Chen
放射治療之惡性腦瘤患者接受另類療法與食物觀念的調查分析/ 陳玉萍曾振淦陳美伶洪志宏曾雁明李弘暉
強度調控放射治療(IMRT)的簡化蒙地卡羅模擬/ 許任玓陳俊丞葉健一李宗其徐椿壽張栢菁
Radiotherapy for the Treatment of Giant Cell Tumor of the Spine: A Report of 3 Cases and Review of the Literature/ Jenny QueChen-Hsing KaoTsung-Chia TsaiLi-Ching LinKuei-Li LinForn-Chia Lin
Treatment Results of Chemotherapy and Radiotherapy in Limited-Stage Small Cell Lung Cancer/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangAi-Yih WangChao-Yuan Huang
早期攝護腺癌之手術治療與放射治療及其預後因子/ 張國楨張慶雄胡渝昌陳建勳
Treatment Outcomes for Epidermoid Carcinoma of the Anal Canal in a Single Institution/ Yen-Chao ChenNagn-Ming TsangFu-Ti ChangJi-Hong Hong
Radiotherapy for Squamous Cell Carcinoma of the Maxillary Sinus/ Y. C. Jeffrey ChaoJian-Sheng JanJin-Ching Lin
早期攝護腺癌之手術治療與放射治療及其預後因子/ 張國楨張慶雄胡渝昌陳建勳
TREATMENT OUTCOMES FOR EPIDERMOID CARCINOMA OF THE ANAL CANAL IN A SINGLE INSTITUTION/ Yen-Chao ChenNagn-Ming TsangFu-Ti ChangJi-Hong Hong
TREATMENT RESULTS OF CHEMOTHERAPY AND RADIOTHERAPY IN LIMITED-STAGE SMALL CELL LUNG CANCER/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangAi-Yih WangChao-Yuan Huang
RADIOTHERAPY FOR SQUAMOUS CELL CARCINOMA OF THE MAXILLARY SINUS/ Y. C. Jeffrey ChaoJian-Sheng JanJin-Ching Lin
強度調控放射治療(IMRT)的簡化蒙地卡羅模擬/ 許任玓陳俊丞葉健一李宗其徐椿壽張?菁
放射治療之惡性腦瘤患者接受另類療法與食物觀念的調查分析/ 陳玉萍曾振淦陳美伶洪志宏曾雁明李弘暉
RADIOTHERAPY FOR THE TREATMENT OF GIANT CELL TUMOR OF THE SPINE: A REPORT OF 3 CASES AND REVIEW OF THE LITERATURE/ Jenny QueCheng-Hsing KaoTsung-Chia TsaiLi-Ching LinKuei-Li LinForn-Chia Lin
SURGERY FOLLOWED BY CONCURRENT CHEMORADIATION WITH WEEKLY CISPLATIN AND ADJUVANT SYSTEMIC CHEMOTHERAPY FOR LOCALLY ADVANCED ESOPHAGEAL CANCER-A PILOT STUDY/ Kuo-Hwa ChangShih-Kai HungHung-Chang LiuCharng-Jer HuangYuen-Liang LaiYu-Jen Chen
 
   
 
   

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