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dvdTaiwan vet雞濾泡顆粒細胞show_pdf.a
   
   
   
     
   
 
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1
題名:TREATMENT RESULTS AND PROGNOSTIC FACTORS OF ESTHESIONEUROBLASTOMA (ENB)     (16點)
嗅神經母細胞瘤治療成果與預後因子
著者:Yu-Ming Wang(王友明) ;Chong-Jong Wang(王重榮) ;Eng-Yen Huang(黃英彥) ;Hui-Chun Chen(陳惠君) ;Li-Min Sun(孫立民) ;Fu-Min Fang(方富民) ;Hsuan-Chih Hsu(許軒之) ;Ching-Yeh Hsiung(熊敬業) ;Yu-Jie Huang(黃郁傑) ;Chang-Yu Wang(汪昶佑)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:知覺神經母細胞瘤 ; 嗅神經母細胞瘤 ; 放射治療 ; Esthesioneuroblastoma ; Olfactory neuroblastoma ; Radiotherapy
刊名:Therapeutic Radiology and Oncology
頁碼:191-198
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

目的:探討有關於嗅神經母細胞瘤之治療成果與預後因子。 材料與方法:自1989 年至2004 年共有21 位診斷為嗅神經母細胞瘤的病患於本科治療,包括14 位男性與7 位女性。病患年齡分布自17 歲至88 歲。我們分析了病患之初期症狀、腫瘤大小、治療方式、與存活時間。10 位病患(48%)接受了傳統定位方式的放射治療, 11 位病患(52%)接受了立體定位順形放射治療。病患之生活活動程度評估依照Karnofsky PerformanceScale(KPS)紀錄。腫瘤之分期依據Kadish 分期。 結果:在分析的21 位病患中2 位病患為A 期, 3 位為B 期, 16 位為C 期。在35 個月的平均追蹤時間後,有4 位病患存活,另4 位存活但有腫瘤。6 位病患發生局部復發,另有5 位病患產生遠端轉移。在15 位發病初期沒有頸部淋巴腫大並沒有接受預防性頸部照射的病患中, 3 位(20%)發生了頸部復發。整體5 年存活率為42% , 5 年無病存活率為17% 。在單變數分析中發現,病患年齡與發病初期之KPS 為影響存活率之預後因子。 結論:我們的研究成果與先前文獻中報告過的成果相近。我們發現病患年齡與KPS 為影響存活之預後因子。由於頸部復發率在嗅神經母細胞瘤的病患中相對甚高,預防性的頸部照射似乎對病患有幫助。
Purpose : To analyze treatment results and prognostic factors of esthesioneuroblastoma (ENB). Materials and methods : Twenty-one patients with diagnosis of ENB treated between 1989 and 2004 were reviewed. There were 14 men and 7 women. Patients’ age ranged from 17 to 88. Presenting symptoms/signs, tumor extent, treatment modalities, survival time, and disease-free survival time were recorded. Ten patients (48%) were treated with conventional two-dimensional technique and 11 (52%) with three-dimensional conformal radiotherapy (3D-CRT). Patient’s performance status was scored with Karnofsky performance scale (KPS). Tumor extent was staged using Kadish system. Results : Of the 21 patients, 2 were Stage A, 3 Stage B, and 16 Stage C. After a mean follow-up time of 35 months, 4 patients are alive with disease and 4 are alive without disease. Locoregional failure occurred in 6 patients and distant metastases were noted in 5 patients. Of the 15 initially node-negative patients who did not receive elective neck irradiation, 3 (20%) failed in the neck. Five-year overall survival rate was 42% and 5-year disease free survival rate was 17%. In univariate analysis, age (_ 60 vs. > 60) and KPS (_ 80 vs. <80) were significant prognostic factors for overall survival (p = 0.019, p = 0.000, respectively) and disease-free survival (p = 0.021, p = 0.001, respectively). Conclusion : Treatment results in our series are compatible with others. We find that age and KPS are significant prognostic factors in predicting the outcome. Due to relatively high incidence of neck failure, elective neck irradiation seems worthy to be considered in selective patients.


    

本卷期目次
Therapeutic Radiology and Oncology
Treatment Results and Prognostic Factors of Esthesioneuroblastoma (ENB)/ Yu-Ming WangChong-Jong WangEng-Yen HuangHui-Chun ChenLi-Min SunFu-Min FangHsuan-Chih HsuChing-Yeh HsiungYu-Jie HuangChang-Yu Wang
第一期下期與第二期上期之子宮頸癌經不同治療模式後的長期生活品質比較/ 許維中詹淑卿鍾娜娜陳宇嘉丁禮莉陳斯榮蔡崇煌王博民謝保群林高德
Radiotherapy in the Management of Localized Classic Kaposi's Sarcoma/ Yao-Ching WangLai-Lei TingChun-Ru ChienSung-Hsin KuoKuo-Ming HuangChao-Yuan HuangMing-Kuen LaiChia-Hsien Cheng
強度調控式放射治療之劑量驗證/ 梁基安蕭安成蘇經雄施文彬潘佳穎
Long-Term Survival with No Evidence of Brain Metastasis in 6 Patients of Limited-Stage Small Cell Lung Cancer Receiving Prophylactic Cranial Irradiation/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangWen-Shan LiuChao-Yuan Huang
動態準直儀葉片於虛擬楔形濾板之研究/ 邱仲峰黃光偉李俊信顏上惠蕭正英陳培勳蔡若婷李玉麟陳良光
Brain Stem Doses for Patients of T3/T4 Nasopharyngeal Carcinoma Treated by Bid Irradiation and Concomitant Chemotherapy/ Stella Y. C. TsaiSkye Hongiun ChengJames Jer-Min JianChao-Ming HuangK. Lawrence YenKwan-Yee ChanSzu-Yun LeuYen-Chun LinNei-Min ChuTran-Der TanCheng-Yee HsiehMei-Hua TsouChing-Yuan LinAndrew T. Huang
Metastatic Cardiac Tumor from Primary Tongue Cancer: A Case Report/ Tzu-Hwei WangWen-Shan Liu
鈷-60輻射污染鋼筋建物居民輻射風險因子之研究/ 蔡顯智許世明張國華陳為立
BRAIN STEM DOSES FOR PATIENTS OF T3/T4 NASOPHARYNGEAL CARCINOMA TREATED BY BID IRRADIATION AND CONCOMITANT CHEMOTHERAPY/ Stella Y. C. TsaiSkye Hon-Giun ChengJames Jer-Min JianChao-Ming HuangK. Lawrence YenKwan-Yee ChanSzu-Yun LeuYen-Chun LinNei-Min ChuTran-Der TanCheng-Yee HsiehMei-Hua TsouChing-Yuan LinAndrew T. Huang
第一期下期與第二期上期之子宮頸癌經不同治療模式後的長期生活品質比較/ 許維中詹淑卿鍾娜娜陳宇嘉丁禮莉陳斯榮蔡崇煌王博民謝保群林高德
TREATMENT RESULTS AND PROGNOSTIC FACTORS OF ESTHESIONEUROBLASTOMA (ENB)/ Yu-Ming WangChong-Jong WangEng-Yen HuangHui-Chun ChenLi-Min SunFu-Min FangHsuan-Chih HsuChing-Yeh HsiungYu-Jie HuangChang-Yu Wang
RADIOTHERAPY IN THE MANAGEMENT OF LOCALIZED CLASSIC KAPOSI'S SARCOMA/ Yao-Ching WangLai-Lei TingChun-Ru ChienSung-Hsin KuoKuo-Ming HuangChao-Yuan HuangMing-Kuen LaiChia-Hsien Cheng
LONG-TERM SURVIVAL WITH NO EVIDENCE OF BRAIN METASTASIS IN 6 PATIENTS OF LIMITED-STAGE SMALL CELL LUNG CANCER RECEIVING PROPHYLACTIC CRANIAL IRRADIATION/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangWen-Shan LiuChao-Yuan Huang
動態準直儀葉片於虛擬楔形濾板之研究/ 邱仲峰黃光偉李俊信?上惠蕭正英陳培勳蔡若婷李玉麟陳良光
強度調控式放射治療之劑量驗證/ 梁基安蕭安成蘇經雄施文彬潘佳穎
鈷-60輻射污染鋼筋建物居民輻射風險因子之研究/ 蔡顯智許世明張國華陳?立
METASTATIC CARDIAC TUMOR FROM PRIMARY TONGUE CANCER: A CASE REPORT/ Tzu-Hwei WangWen-Shan Liu
 
   
 
   

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