原名「台灣學術線上」
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1
題名:THE EFFICACY OF RADIATION THERAPY FOR KELOID AND HYPERTRROPHIC SCAR: THE EXPERIENCE OF NINE CASES     (22點)
利用放射線治療瘢瘤或肥厚疤痕的成效評估:九例患者的經驗
著者:Yu-Wen Rubin Wang(王裕文) ;How-Ran Guo(郭浩然) ;Chin-Wu Cheng(鄭智武)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:瘢瘤 ; 肥厚疤痕 ; 放射治療 ; Keloid ; Hypertrophic scar ; Radiotherapy
刊名:Therapeutic Radiology and Oncology
頁碼:149-159
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

目的:報告一家教學醫院用放射線治療術後瘢瘤的經驗。 材料與方法:我們收集自 1999 到 2003 年在本院執行瘢瘤或肥厚疤痕患者在術後進行放療的結果,並分析當中可能的因素。 結果:這段期間共有九個患者的治療被觀察,其中一位男性,八位女性。五位對其結果感到滿意,二位還可以,二位感到失望。感到失望的患者中,一位的瘢瘤長成腫塊狀,另一位開刀過了 17 天才來放療。感到滿意的患者中,一位開刀過了 6 天才來放療,其他則開過刀 2 天內就開始放療。總共九個患者 中,8 位接受了 15 Gy,分五次照射完畢;另一位接受了12 Gy,分四次照射完畢。研究期間沒有看到次發性惡性腫瘤是因為放療引起的。經過分析所有的變數之後發現初始症狀有醜型問題者和治療滿意度有相關,但沒有一個變數和預後結果有關。 結論:劑量在 12 到 15 Gy 間,分 4 到 5 次照射,對瘢瘤或肥厚疤痕的術後放射治療是適宜的。術後應在 2-3 天內即開始放療。就算在此條件下放療,治療反應仍可能不佳,尤其是已經長成腫塊狀的瘢瘤。
Purpose : To report the experience of postoperative radiation therapy (RT) for keloid at a teaching hospital. Material and Methods : We recruited patients with keloid or hypertrophic scar lesions who received excision and postoperative RT from 1999 to 2003 at a teaching hospital. We use 6 MeV electron beam covered with 0.5-1 cm Superflap as bolus to enhance skin dose, and the electron beam margin was designed as 0.5 to 1 cm from re-operative suture line area. All of them were treated with 15 Gy of RT in five fractions in consecutive days, except one who had problems in scheduling the last treatment and received 12 Gy in four fractions. We summarized information on their outcomes and evaluated the possible prognostic factors. Results : A total of nine patients were observed during the study period, including one man and eight women. Five of them were satisfied with their outcomes, two had fair outcome, and two felt disappointed. Of the two disappointed patients, one had a gross keloid, and the other had an elapsed time of 17 days between excision and radiation. One of the patients with satisfactory outcome, however, had an elapsed time of 6 days. All the other six patients who had satisfactory or fair outcomes started RT within 2 days after surgery. Eight patients received 15 Gy in five fractions, and one received 12 Gy in four fractions. No second malignancy was observed during the study period. Among all variables evaluated, ugly as the initial symptom was the only significant factor associated with satisfaction, but none was associated with the outcome. Conclusion : The dose-fractions between 12 and 15 Gy in four or five fractions are feasible in postoperative RT for keloid or hypertrophic scar. Starting the RT within 2 to 3 days should be suggested after excision. Unsatisfactory response is still possible under this timing and dose-fractions, especially for gross lesions.


    

本卷期目次
Therapeutic Radiology and Oncology
The Efficacy of Radiation Therapy for Keloid and Hypertrrophic Scar: The Experience of Nine Cases/ Yu-Wen Rubin WangHow-Ran GuoChin-Wu Cheng
快速成型技術直接製作放射治療填充物之效能評估/ 吳錦榕孫述平蕭世禎彭秋萍游佩潔紀淑妮陳柏婷林家弘薛文雅郭名傑詹淑如
Verification of Patient Setup Error in Tomotherapy through Image Guided Radiation Therapy (IGRT) Procedure/ Shao-Ti LiWen-Shan LiuYing-Hsiang ChouPei-Wei HsiungHsiu-Ting HsuHsi-Chang Chang
Clinical Features and Management of Distant Metastases from Nasopharyngeal Carcinoma/ Chia-Chun HuangMu-Tai LiuCheng-Chuan ChangMu-Kuan ChenTung-Hao ChangChu-Ping PiChih-Chieh Hsu
The Treatment Results of Unknown Primary Head and Neck Cancers without Epstein-Barr Virus Infection/ Bing-Shen HuangJi-Hong HongPing-Ching PaiChun-Chieh WangNgan-Ming Tsang
蒙地卡羅方法模擬於臨床電子直線加速器之電子射源項參數研究/ 紀金輝張國平蕭安成陳信雄楊世能潘榕光梁基安趙敏
Long-Term Outcome of Postoperative Adjuvant Radiotherapy for Thymoma/ Huei-Chun LuJian-Sheng JanJin-Ching Lin
Early-Stage Esophageal Squamous Cell Carcinoma Adjacent to Cirrhosis-Related Varices: A Case Report/ Yu-Nong WangDai-Wei LiuHsi-Sheng ChsiaWen-Lin Hsu
LONG-TERM OUTCOME OF POSTOPERATIVE ADJUVANT RADIOTHERAPY FOR THYMOMA/ Huei-Chun LuJian-Sheng JanJin-Ching Lin
CLINICAL FEATURES AND MANAGEMENT OF DISTANT METASTASES FROM NASOPHARYNGEAL CARCINOMA/ Chia-Chun HuangMu-Tai LiuCheng-Chuan ChangMu-Kuan ChenTung-Hao ChangChu-Ping PiChih-Chieh Hsu
VERIFICATION OF PATIENT SETUP ERROR IN TOMOTHERAPY THROUGH IMAGE GUIDED RADIATION THERAPY (IGRT) PROCEDURE/ Shao-Ti LiWen-Shan LiuYing-Hsiang ChouPei-Wei HsiungHsiu-Ting HsuHsi-Chang Chang
蒙地卡羅方法模擬於臨床電子直線加速器之電子射源項參數研究/ 紀金輝張國平蕭安成陳信雄楊世能潘榕光梁基安趙敏
快速成型技術直接製作放射治療填充物之效能評估/ 吳錦榕孫述平蕭世禎彭秋萍游佩潔紀淑妮陳柏婷林家弘薛文雅郭名傑詹淑如
THE EFFICACY OF RADIATION THERAPY FOR KELOID AND HYPERTRROPHIC SCAR: THE EXPERIENCE OF NINE CASES/ Yu-Wen Rubin WangHow-Ran GuoChin-Wu Cheng
EARLY-STAGE ESOPHAGEAL SQUAMOUS CELL CARCINOMA ADJACENT TO CIRRHOSIS-RELATED VARICES: A CASE REPORT/ Yu-Nong WangDai-Wei LiuHsi-Sheng ChsiaWen-Lin Hsu
THE TREATMENT RESULTS OF UNKNOWN PRIMARY HEAD AND NECK CANCERS WITHOUT EPSTEIN-BARR VIRUS INFECTION/ Bing-Shen HuangJi-Hong HongPing-Ching PaiChun-Chieh WangNgan-Ming Tsang
 
   
 
   

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