原名「台灣學術線上」
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1
題名:EVALUATION OF CYBERKNIFE TREATMENT PLANNING FOR PROSTATE CANCER USING THE CONFORMAL INDEX AND THE TUMOR CONTROL PROBABILITY     (20點)
以劑量包覆順型度數學模型和腫瘤控制機率模式評估攝護腺癌在放射手術電腦刀治療計畫系統
著者:Chia-Chun Kuo(郭嘉駿) ;Hsiao-Wei Yu(余孝緯) ;Kuang-Wei Huang(黃光偉) ;Chiu-Ping Chen(陳秋萍) ;Tao-Sang Chung(鍾道生) ;Jeng-Fong Chiou(邱仲峰) ;Jo-Ting Tsai(蔡若婷)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:腫瘤包覆順型度 ; 腫瘤控制機率模式 ; 立體定位放射線手術 ; 電腦刀 ; Conformity index ; Tumor control probability ; Stereotactic radiosurgery ; CyberKnife
刊名:Therapeutic Radiology and Oncology
頁碼:301-310
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

目的:本研究在於利用劑量包覆順型度數學模型,分析電腦刀放射治療技術輻照區域劑量與周圍器官體積彼此間順型度之關係。配合腫瘤控制機率公式運算分析攝護腺癌經放射治療後腫瘤控制機率,以期更能適用於電腦刀治療計畫的分析。 材料與方法:本研究回溯性收集六名攝護腺腫瘤患者接受低分次電腦刀立體定位放射治療計畫。給予劑量分別為 37.5 Gy 分五次治療,42 Gy 分五次治療,和 32 Gy 分四次治療。計算劑量包覆順型度及腫瘤控制機率,並分析計算結果以作為評估電腦刀計畫系統的參考。 結果:電腦刀治療計畫系統本身所提供的劑量包覆順型度計算值在腫瘤控制機率達 98.3% 以上時均在 1.483 以下。而經過以週遭重要器官加入考量的模式計算後,增加劑量包覆順型度的差異性提供作為治療計畫的評估。 結論:放射線手術治療計畫給予較高的生物等效劑量,故適用於電腦刀劑量包覆順型度模式,必須能兼顧分析放射治療劑量區最佳的腫瘤體積包覆特性,和擴散到周圍的正常組織高劑量分佈。本文中所運算的模式可以用來評估及比較放射治療計畫。
Purpose : This study was to evaluate the feasibility of dose conformity and tumor control probability calculated for CyberKnifeR hypofractionated planning for prostate cancer. Materials and Methods : Six patients with early prostate cancer were included in this retrospective study. They received stereotactic hypofractionation radiotherapy by CyberKnifeR. The dose prescriptions were 37.5 Gy in 5 fractions, 42 Gy in 5 fractions, or 32 Gy in 4 fractions. Dose conformity was calculated with three parameters: the conformity index (CI), the new conformity index (nCI) and the modified conformal index (mCOIN). A statistical analysis of the tumor control probability (TCP) was also calculated. Results : The CI and nCI of the CyberKnifeR treatment planning system are all under 1.483. All the calculated TCP values were greater than 98.3%. We added the factors pertaining to the critical organ and obtained the mCOINs. The mCOIN values were listed to compare the quality of treatment plans. Conclusion : The conformity index value can be used to evaluate the quality of radiosurgery planning. The mCOIN values are also feasible to compare the plans.


    

本卷期目次
Therapeutic Radiology and Oncology
A Case of Abdominal Tumor with Unusual Presentation/ Chi-Fu HungChien-Ru LiuJyh-Der Leu
型號FWT-70-40(M)劑量計應用於BNCT輻射場的加馬劑量度量/ 許彬杰劉鴻鳴黎雪萍劉朝錦蔡文旗江祥輝
Evaluation of Cyberknife Treatment Planning for Prostate Cancer using the Conformal Index and the Tumor Control Probability/ Chia-Chun KuoHsiao-Wei YuKuang-Wei HuangChiu-Ping ChenTao-Sang ChungJeng-Fong ChiouJo-Ting Tsai
放射腫瘤癌患接受西醫、中醫與另類療法的相關性調查分析/ 陳玉萍曾振淦曾雁明洪志宏
Moderately Differentiated Neuroendocrine Carcinoma of the Larynx: A Case Report and Review of the Literatures/ Tsai-Ying HuangDai-Wei LiuYung-Hsiang HsuHsi-Sheng ChsiaWen-Lin Hsu
Adjuvant Chemoradiation for Surgical Resected Gastric Cancer Patients: CGH Experience/ Su-Zun ShawYung-Chuan SungChing-Shui HuangMin-Yen ShiHan-Ting LiuPei-Chieh YuChing-Jung Wu
Clinical Outcome of Postoperative Intensity-Modulated Radiotherapy for Esophageal Cancer/ Hui-Ling YehChung-Ping HsuJin-Ching LinJian-Sheng JanJai-Fu LinChen-Fa ChangChing-Te Wu
鼻咽癌病患經放射治療後生活品質之急性變化/ 許维中丁禮莉陳宇嘉詹淑卿王博民鍾娜娜劉博仁林高德
Adenoid Cystic Carcinoma of the Trachea Treated with Post-operative Chemoradiotherapy and Metronomic Chemotherapy: A Case Report/ Gwo-Che HuangCharng-Jer HuangKou-Hwa ChangYu-Jen Chen
鼻咽癌病患經放射治療後生活品質之急性變化/ 許?中丁禮莉陳宇嘉詹淑卿王博民鍾娜娜劉博仁林高德
CLINICAL OUTCOME OF POSTOPERATIVE INTENSITY-MODULATED RADIOTHERAPY FOR ESOPHAGEAL CANCER/ Hui-Ling YehChung-Ping HsuJin-Ching LinJian-Sheng JanJai-Fu LinChen-Fa ChangChing-Te Wu
ADJUVANT CHEMORADIATION FOR SURGICAL RESECTED GASTRIC CANCER PATIENTS: CGH EXPERIENCE/ Su-Zun ShawYung-Chuan SungChing-Shui HuangMin-Yen ShiHan-Ting LiuPei-Chieh YuChing-Jung Wu
放射腫瘤癌患接受西醫、中醫與另類療法的相關性調查分析/ 陳玉萍曾振淦曾雁明洪志宏
EVALUATION OF CYBERKNIFE TREATMENT PLANNING FOR PROSTATE CANCER USING THE CONFORMAL INDEX AND THE TUMOR CONTROL PROBABILITY/ Chia-Chun KuoHsiao-Wei YuKuang-Wei HuangChiu-Ping ChenTao-Sang ChungJeng-Fong ChiouJo-Ting Tsai
型號FWT-70-40(M)劑量計應用於BNCT輻射場的加馬劑量度量/ 許彬杰劉鴻鳴黎雪萍劉朝錦蔡文旗江祥輝
MODERATELY DIFFERENTIATED NEUROENDOCRINE CARCINOMA OF THE LARYNX: A CASE REPORT AND REVIEW OF THE LITERATURES/ Tsai-Ying HuangDai-Wei LiuYung-Hsiang HsuHsi-Sheng ChsiaWen-Lin Hsu
A CASE OF ABDOMINAL TUMOR WITH UNUSUAL PRESENTATION/ Chi-Fu HungChien-Ru LiuJyh-Der Leu
ADENOID CYSTIC CARCINOMA OF THE TRACHEA TREATED WITH POST-OPERATIVE CHEMORADIOTHERAPY AND METRONOMIC CHEMOTHERAPY: A CASE REPORT/ Gwo-Che HuangCharng-Jer HuangKou-Hwa ChangYu-Jen Chen
 
   
 
   

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