原名「台灣學術線上」
包含TAO期刊庫 + TAO書籍庫 + 論文 + 史料文獻
首頁 | 關於TAO | 瀏覽 | 進階查詢 | 參考工具 | 會員服務 | 已購專書 | RSS服務 | 電子報 | FAQ  
查詢範圍:
   
查詢模式:
熱門查詢詞:
dvdBlood Warm墾丁國家公園水域活動舌尖與筆尖的對話
   
   
   
     
   
 
項次 書目
1
題名:Characteristics, Advantages and Limitations of a Treatment Planning System for Gamma Knife Radiosurgery     (18點)
加馬刀放射手術治療計畫的特色優點及限制
著者:Ling-Wei Wang(王令瑋) ;Cheng-Ying Shiau(蕭正英) ;Wen-Yuh Chung(鍾文裕) ;David Hung-Chi Pan(潘宏基) ;Wan-Yuo Guo(郭萬祐) ;Yuh-Ling Lee(李玉麟) ;Sang-Hue Yen(顏上惠) ;Kuang Y. Chen(陳光耀)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:放射手術 ; 加馬刀 ; 治療計畫 ; Radiosurgery ; Gamma Knife ; Treatment planning ; KULA
刊名:Therapeutic Radiology and Oncology
頁碼:69-77
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

本文主旨在介紹加馬刀治療計畫KULA系統的特色,並以一復發鼻咽為例,討論臨床上使用該系統之優缺點。 自1993年3月起本院開始以立體定位加馬手術刀治療腦內之動靜脈畸型,聽神經瘤及其他顱內良性或惡性腫瘤。為計算201個鈷六十射源的合成劑量,此種放射手術應用了特別設計的治療計畫電腦軟體(KULA)。治療的原理是堆積不同大小之照射聚焦中心(shots)來涵蓋腫瘤範圍。KULA使用三度空間劑量計算,並以水平面、冠狀切面、矢狀切面等二度空間的方式呈現劑量分布圖。不但可以用單一聚焦中心治療較小的腫瘤,堆積最多達十二個聚焦中心也可治療較大的腫瘤。計算結果可獲得相當良好的精確度及令人滿意的劑量分佈,但對於體積較大且形狀不規則的腫瘤,例如復發於顱底的鼻咽癌,治療計畫所花的時問相當冗長。主要原因之一是KULA系統在輸入指令,執行計算及顯示等劑量曲線圖的功能上,效率不佳。它未能將影像檢查資料納入計畫系統內,也沒有提供使用者與圖形的介面。雖然經過多次的修正後仍能得到滿意意的劑量分布,但所費的時聞相當不經濟。在新一代的治療計畫軟體尚未啟用前,熟悉KULA系統的特性及聚焦中心的配置組合原則,是進行高效率治療計畫的唯一途徑。
Stereotactic radiosurgery refers to the use of small, well-collimated beams of ionizing radiation to ablate intracranial lesions. In our hospital radiosurgery with the Leksell Gamma Knife was used to treat AVM, acoustic neuroma, meningioma, glioma and other benign or malignant brain tumors. To deal with 201 cobalt-60 sources of the Gamma Knife, the complex dosimetry was performed using specially developed computer software (KULA). The treatment planning with KULA for a recurrent nasopharyngeal cancer after external beam radiotherapy is presented. After initial rough planning with 12 shots to cover the tumor, repeated revisions of coordinates and weights of most shots resulted in a 50% isodose curve matching the tumor contour in 3 dimensions. The possibility of neurological complication is low due to the relative low dose (<30%) to the neighboring optic nerve and brain stem. Though the result of this laborious and prolonged treatment planning is good, the amenity and efficiency of using KULA are unsatisfactory for this large and irregular shaped tumor. When stacking of multiple isocenters or shots in 3 dimensions to fill the tumor volume, the melded isodose curves can be very differnt from the simple combination of individual curves and trials and errors are inevitable. For efficient planning of large and irregular shaped tumors with KULA, it is essential to be familiar with the principle of allocation and methods of fine adjustment of parameters of shots.


    

本卷期目次
Therapeutic Radiology and Oncology
Estimation of High-Energy Primary Photon-Induced Doses for Non Charged Particle Equilibrium Conditions/ Max M. ChaoGeorge E. Chabot
Conservation Therapy of Breast Cancer/ Andrew Y. H. YoungChi-Yuan YehYeun-Liang LaiKou-Hwa ChangChang-Hung ChungYi-Cherng Lai
放射線診斷和治療學在中國大陸和台灣的發展史/ 陳光耀
全頭皮放射治療技術之劑量術評估/ 葉健一湯國政賴易成賴允亮
維生素丙對於放射線傷害之修復與預防效應的體外研究/ 許文林黃經民任益民盧昭元趙壯飛
白葉素在癌症化學治療上的用途/ 周寬基周絢蘭季匡華陳光耀
Optimization of Position and Exposure Time of Radioactive Source in High-Dose-Rate Afterloading Brachytherapy/ Liung S. ChaoSang H. YenYuh L. LeeCheng-Ying ShiauFu D. ChenKuang Y. Chen
Medulloblastoma: The Treatment Results and Literature Review/ Meng-Hao WuYuen-Liang LaiChi-Yuan YebChang-Hung ChungChung-Yu KaoKuo-Hwa Chang
Primary Malignant Lymphoma of the Breast-Three Cases Report/ Meng-Hao WuChung-Yu KaoWen-Haw SuYuen-Liang LaiChang-Hung Chung
抗癌藥Taxol與放射線的放射增敏作用:尋找最佳配合的理論基礎/ 季匡華周寬基張立平吳樂榮陳富都陳光耀
Characteristics, Advantages and Limitations of a Treatment Planning System for Gamma Knife Radiosurgery/ Ling-Wei WangCheng-Ying ShiauWen-Yuh ChungDavid Hung-Chi PanWan-Yuo GuoYuh-Ling LeeSang-Hue YenKuang Y. Chen
Quality Assurance in Modern Sophisticated LINAC Radiotherapy/ Max M. ChaoLiung S. ChaoYuh L. LeeSang H. YenKuang Y. Chen
放射線診斷和治療學在中國大陸和台灣的發展史/ 陳光耀
抗癌藥Taxol與放射線的放射增敏作用:尋找最佳配合的理論基礎/ 季匡華周寬基張立平吳樂榮陳富都陳光耀
維生素丙對於放射線傷害之修復與預防效應的體外研究/ 許文林黃經民任益民盧昭元趙壯飛
Medulloblastoma: The Treatment Results and Literature Review/ Meng-Hao WuYuen-Liang LaiChi-Yuan YehChang-Hung ChungChung-Yu KaoKuo-Hwa Chang
Conservation Therapy of Breast Cancer/ Andrew Y. H. YoungChi-Yuan YehYeun-Liang LaiKou-Hwa ChangChang-Hung ChungYi-Cherng Lai
Optimization of Position and Exposure Time of Radioactive Source in High-Dose-Rate Afterloading Brachytherapy/ Liung S. ChaoSang H. YenYuh L. LeeCheng-Ying ShiauFu D. ChenKuang Y. Chen
Estimation of High-Energy Primary Photon-Induced Doses for Non Charged Particle Equilibrium Conditions/ Max M. ChaoGeorge E. Chabot
Quality Assurance in Modern Sophisticated LINAC Radiotherapy/ Max M. ChaoLiung S. ChaoYuh L. LeeSang H. YenKuang Y. Chen
全頭皮放射治療技術之劑量術評估/ 葉健一湯國政賴易成賴允亮
Characteristics, Advantages and Limitations of a Treatment Planning System for Gamma Knife Radiosurgery/ Ling-Wei WangCheng-Ying ShiauWen-Yuh ChungDavid Hung-Chi PanWan-Yuo GuoYuh-Ling LeeSang-Hue YenKuang Y. Chen
白葉素在癌症化學治療上的用途/ 周寬基周絢蘭季匡華陳光耀
Primary Malignant Lymphoma of the Breast-Three Cases Report/ Meng-Hao WuChung-Yu KaoWen-Haw SuYuen-Liang LaiChang-Hung Chung
 
   
 
   

與TAO合作 | 隱私與版權聲明 | 聯絡方式 | 下載Adobe Reader
地址:台北市中正區(100)北平東路30-12號3樓
電話:(02)2393-6968 傳真:(02)2393-6877
Email: service@wordpedia.com
Wordpedia Family: 學校、企業版入口 | 遠流影音館
Copyright©2011 Wordpedia Co., Ltd. All Rights Reserved.