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1
題名:Curative Radiotherapy for Vocal Cord Carcinoma     (12點)
喉癌的放射治療
著者:Yih-Chyang Weng(翁益強) ;Jin-Ching Lin(林進清) ;Jian-Sheng Jan(詹建勝)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:喉癌 ; 放射治療 ; Vocal cord carcinoma ; Radiotherapy
刊名:Therapeutic Radiology and Oncology
頁碼:187-192
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

放射治療對喉癌患者不僅有好的局部治療效果,尤其能良好保持患者的說話功能。從1 9 8 3 年2 月到1992 年12 月, 共有75 位喉癌患者在台中榮總單獨接受放射治療, 其中男性的位, 女性6 位, 平均年齡6 4 歲。 75 位患者中, 40 位是原位腫瘤第1 期, 22 位是原位腫瘤第2 期, 8 位是原位腫瘤第3 期, 和5 位是原位腫瘤第4期。男外75五位患者中有5位有頸部淋巴轉移,其中有一位是原位腫瘤第1期, 一位原位是腫瘤第2期,一位是原位腫瘤第3期,二位是原位腫瘤第4期。 大部分患者放射治療是以每日2 0 0 至2 2 0 cGy' 兩倒對照, 總劑量為6,000 至6,600 cGy 。有8 位患者是以每日放射治療兩次, 每次1 5 0 至1 7 0 cGy' 兩側對照, 總劑量5 ,800 至7,400 cG y 。以及另一位患者是以兩段式放射治療,每日是以3 0 0 cGy' 兩側對照, 每一階段照射10 次, 中間休息兩週, 總劑量共為6 , 0 0 0 cGy 。 幾乎所有患者都能很快從放射治療急性反應中恢復,除了一位患者治療後兩個月內發生嚴重聲帶浮腫,及另兩位患者在治療最後兩週因肺癌過逝。 經放射治療後, 發聲功能保留率為9 6 % 。原位腫瘤第一期5年無病存活率為8 6 % '第二期為8 0 % '第三期為7 5 % '而第四期患者都在1 8個月內過逝,其p值小於0 . 0 0 1 。對於無淋巴轉移之患者5 年無病存活率為8 2 % '而有淋巴轉移之患者都在30個月內過逝,其p值小於0 . 0 0 1 。因此原位腫瘤第四期與有淋巴轉移之,患者的預後十分差。男外針對性別和年齡區分來探討患者5 年無病存活率,則無明顯差別。 5 位接受每日放射治療兩次的早期患者, 經治療後, 目前追蹤兩年以上, 暫無病症, 初期療效不錯,但需進一步觀察。
Radiotherapy for vocal cord carcinoma plays an important role in controlling the primary tumors and regional lymph nodes and preserving the voice. From February 1983 to December 1992, 75 patients wit h vocal cord carcinoma were treated by curative radiot he rapy alone at VGHTC. 69 patients wer e male and 6 patients were female. The median age was 64 years old. There were 40 of 75 patients with Tl, 22 wit h T2, 8 wit h T3 and 5 with T4. 5 of 75 patients had positive lymph node metastases (1 of 5 patients with Tl, 1 wit h T2, 1 with T3, and 2 with T4). External beam radiotherapy was mostly delivered wit h bilateral opposing portals and a single daily fraction between 200 cGy and 220 cGy per day, up to a total dose between 6000 cGy and 6600 cGy. 8 patients were treated with bilateral opposing portals and hyperfractionation using 150 cGy to 170 cGy bid per day, up to a total dose between 5800 cGy t o 7400 cGy. 1 patient was treated with bilateral opposing portals and split course technique of 300 cGy per day with two weeks interval, up to 6000 cGy. Almost all patients recovered from ac ute reactions of radiotherapy soon except one patient with acute laryngeal edema in 2 months post radiotherapy and two patien ts with acute pneumonia due to cachexia in the last days of radiotherapy. The vocal function preservation rate is about 96%. The 5-year diseasefree survival rates in st age Tl, T2 and T3 were 86%, 80% and 75% re spectively and T4 patients all died in 18 months. The P value is less than 0.001. The 5-year disease-free survival rate in stage NOwas 82% but N positive patients died in 30 months post radiotherapy. The P value is less than 0.001. Therefore T4 stage and N positive were obvious ly poorly prognostic factors. No significant differences of 5-year disease-free surv ival rates between male and female or younger and older age were noted a nd P values were 0.36 and 0.98 respectively. 5 patients with early stage were treated by hyperfractionation radiotherapy from 1991 to 1992. They ha ve had good local control with a minimum follow-up of 24 months but it needs more time to follow up.


    

本卷期目次
Therapeutic Radiology and Oncology
Results of Radiation Therapy for Regional Stage T4 Nasopharyngeal Carcinoma/ Chi-Yuan YehYuen-Liang LaiChang-Hung ChungKou-Hwa ChangYih-Cherng Lai
醫用直線加速器系統構造與保養作業簡介/ 李財福梁雲王重榮許順能黃置柔吳嘉明
Patterns of Pelvic Recurrence and Results of Salvage Treatment with Radiation Therapy for Recurrent Rectal Carcinoma/ Chong-Jong WangStephen Wan LeungHui-Chun ChenLi-Min SunFu-Min Fang
接受輻射治療之鼻咽腫瘤患者其視綱膜病變之評估/ 張東杰林淵謙陳墩祿楊克仁陳麗惠湯國政
西藏癌症與衛生醫療現況/ 顏上惠劉淑娟陳光耀
Curative Radiotherapy for Vocal Cord Carcinoma/ Weng Yih-ChyangJin-Ching LinJian-Sheng Jan
如何使用模擬攝影機之擋影托盤(shadow tray)确認擋塊位置/ 何聖佑鄭秀成雷德
維生素丙對鼷鼠放射線口腔黏膜炎修復與預防效應之研究/ 許文林黃經民任益民施榕平李恒昇李偉華
The Role of Epstein-Barr Virus Infection and the Immunocompetence of Patients with Nasopharyngeal Cancer/ Kuan-Chih ChowKuang Y. Chen
Postoperative Radiotherapy for Malignant Gliomas/ Shyh-An YehStephen Wan LeungLi-Mm SunChong-Jong WangHuey-Jiun ChenFu-Min Fang
Study on Radiation Safety of High Dose Rate Multiple Cobalt-60 Sources Teletherapy Machine/ Sang-Hue YenYuh-Lin LeeLiung S. ChaoMax M. ChaoDavid HC PanKuang Y. Chen
Postoperative Low Dose Single Fraction Irradiation for Prevention of Heterotopic Bone Formation after Hip Surgery/ Le-Jung WuSang-Hue YenTain-Hsiung ChenLing-Wei WangKwan-Hwa ChiKuang Y. Chen
C型行為與癌的關系-癌症心理學書評-/ 陳光耀
維生素丙對所鼷鼠放射線口腔黏膜炎修復與預防效應之研究/ 詩文林黃經民任益民施榕平李恆昇李偉華
Curative Radiotherapy for Vocal Cord Carcinoma/ Yih-Chyang WengJin-Ching LinJian-Sheng Jan
Results of Radiation Therapy for Regional Stage T4 Nasopharyngeal Carcinoma/ Chi-Yuan YehYuen-Liang LaiChang-Hung ChungKou-Hwa ChangYih-Cherng Lai
接受輻射治療之鼻咽腫瘤患者其視網膜病變之評估/ 張東杰林淵謙陳墩禄楊克仁陳麗惠湯國政
Postoperative Low Dose Single Fraction Irradiation for Prevention of Heterotopic Bone Formation after Hip Surgery/ Le-Jung WuSang-Hue YenTain-Hsiung ChenLing-Wei WangKwan-Hwa ChiKuang Y. Chen
Patterns of Pelvic Recurrence and Results of Salvage Treatment with Radiation Therapy for Recurrent Rectal Carcinoma/ Chong-Jong WangStephen Wan LeungHui-Chun ChenLi-Min SunFu-Min Fang
Postoperative Radiotherapy for Malignant Gliomas/ Shyh-An YehStephen Wan LeungLi-Min SunChong-Jong WangHuey-Jiun ChenFu-Min Fang
Study on Radiation Safety of High Dose Rate Multiple Cobalt-60 Sources Teletherapy Machine/ Sang-Hue YenYuh-Lin LeeLiung S. ChaoMax M. ChaoDavid HC PanKuang Y. Chen
The Role of Epstein-Barr Virus Infection and the Immunocompetence of Patients with Nasopharyngeal Cancer/ Kuan-Chih ChowKuang Y. Chen
如何使用模擬攝影機之擋影托盤(shadow tray)確認擋塊位置/ 何聖佑鄭秀成雷德
醫用直線加速器系統構造與保養作業簡介/ 李財福梁雲王重榮許順能黃置柔吳嘉明
西藏癌病與衛生醫療現況/ 顏上惠劉淑娟陳光耀
C型行為與癌的關係--癌症心理學書評--/ 陳光耀
 
   
 
   

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