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1
題名:Postoperative Low Dose Single Fraction Irradiation for Prevention of Heterotopic Bone Formation after Hip Surgery     (14點)
利用手術後單劑量照射預防髖關節異位骨化
著者:Le-Jung Wu(吳樂榮) ;Sang-Hue Yen(顏上惠) ;Tain-Hsiung Chen(陳天雄) ;Ling-Wei Wang(王令瑋) ;Kwan-Hwa Chi(季匡華) ;Kuang Y. Chen(陳光耀)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:髖關節 ; 異位骨化 ; 放射治療 ; Hip joints ; Heterotopic ossification ; Radiotherapy
刊名:Therapeutic Radiology and Oncology
頁碼:209-215
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

體關節異位骨化是鵲關節手術後常見之併發症, 而有高危險因子的病患發生的比率更高, 可高達50% 。所謂高危險因子包括值直性脊椎炎、骨關節炎、體關節骨折、體關節多次手術, 異位骨化之既往歷。而預防高危險群病患手術後發生體關節異位骨化的方法有手術改良,藥物治療及放射治療等三種方式。于術改良尚未證實有效,藥物治療雖然有效但需長期服用且易產生副作用,然而放射治療不僅有效且耗時短而為臨床上常用之方式。從1 9 89年至1 9 94年,台北榮總共治療了15位病人(18處體關節) , 這些病人包括了僵直性脊椎炎( 1 2例)、骨關節炎(1例卜輯部骨折( 2例卜體關節多次手術( 3例) , 有異位骨化之既往歷( 1 例) , 有3 例危險因子超過2 個以上。這1 5 例均為男性, 年齡分佈從2 4 至7 0 歲,所作之手術包括全關節置換(14 處關節卜人工關節修補( 3 處關節卜骨折接合術(1 處關節卜放射治療則在手術後6天內實施。利用加馬線及一千萬伏特X光以前後對稱照野施以單次照射,照射範圍包括攬臼, 股骨頭上半部及周圍軟組織, 照射劑量是5 或7 格雷。治療後追蹤4 到6 6 個月, 期間有2 處聽關節發生異位骨化,另有1處已發生異位骨化之關節則未繼續惡化。此外無1例發生併發症及異位骨化引起之功能不良。我們之經驗顯示手術後單劑量照射對預防體關節異位骨化是有效而安全的治療。
Purpose: To investigate retrospectively the effects of postoperative low-dose single fraction irradiation in prevention of ectopic bone formation after hip surgery in high-risk patients. Materials and Methods: From 1989 to 1994 fif teen patients (18 hips) were treated with single-dose irradiation to hip joints after hip surgery in an attempt to prevent heterotopic bon e formation. Of these patients, there were 12 patients with ankylosing spondilitis, 1 patient with osteoarthritis, 2 patients with bony fractures, 3 patients post multiple surgical procedures, and 1 patient with past history of ectopic bone formation. These patients received surgical procedures of primary total-hip arthroplast y (14 hips), revision of arthroplasty (3 hips), or open reduction of acet abular fracture (1 hip). Radiotherapy was delivered with either Cobalt -60 gamma ray (4 patients) or 10 MV X-ray (11 patients) at midplane doses of 5 or 7 Gy several hours to 6 days after operation. Results: New ectopic bone formation was found in 2 patients (2 hips), while 1 patient (1 hip) ha s stable disease, with a follow-up time from 4 to 66 months (median =31 months). Neither functional disability nor complication related to heterotopic ossification and irradiation developed. Conclusion: Postoperative low-dose single fraction irradiation with 5 or 7 Gy is an effective and safe procedure to prevent heterotopic bone formation in high-risk patients after hip surgery.


    

本卷期目次
Therapeutic Radiology and Oncology
Study on Radiation Safety of High Dose Rate Multiple Cobalt-60 Sources Teletherapy Machine/ Sang-Hue YenYuh-Lin LeeLiung S. ChaoMax M. ChaoDavid HC PanKuang Y. Chen
Curative Radiotherapy for Vocal Cord Carcinoma/ Weng Yih-ChyangJin-Ching LinJian-Sheng Jan
如何使用模擬攝影機之擋影托盤(shadow tray)确認擋塊位置/ 何聖佑鄭秀成雷德
維生素丙對鼷鼠放射線口腔黏膜炎修復與預防效應之研究/ 許文林黃經民任益民施榕平李恒昇李偉華
The Role of Epstein-Barr Virus Infection and the Immunocompetence of Patients with Nasopharyngeal Cancer/ Kuan-Chih ChowKuang Y. Chen
Postoperative Low Dose Single Fraction Irradiation for Prevention of Heterotopic Bone Formation after Hip Surgery/ Le-Jung WuSang-Hue YenTain-Hsiung ChenLing-Wei WangKwan-Hwa ChiKuang Y. Chen
C型行為與癌的關系-癌症心理學書評-/ 陳光耀
Patterns of Pelvic Recurrence and Results of Salvage Treatment with Radiation Therapy for Recurrent Rectal Carcinoma/ Chong-Jong WangStephen Wan LeungHui-Chun ChenLi-Min SunFu-Min Fang
Postoperative Radiotherapy for Malignant Gliomas/ Shyh-An YehStephen Wan LeungLi-Mm SunChong-Jong WangHuey-Jiun ChenFu-Min Fang
Results of Radiation Therapy for Regional Stage T4 Nasopharyngeal Carcinoma/ Chi-Yuan YehYuen-Liang LaiChang-Hung ChungKou-Hwa ChangYih-Cherng Lai
醫用直線加速器系統構造與保養作業簡介/ 李財福梁雲王重榮許順能黃置柔吳嘉明
接受輻射治療之鼻咽腫瘤患者其視綱膜病變之評估/ 張東杰林淵謙陳墩祿楊克仁陳麗惠湯國政
西藏癌症與衛生醫療現況/ 顏上惠劉淑娟陳光耀
維生素丙對所鼷鼠放射線口腔黏膜炎修復與預防效應之研究/ 詩文林黃經民任益民施榕平李恆昇李偉華
Curative Radiotherapy for Vocal Cord Carcinoma/ Yih-Chyang WengJin-Ching LinJian-Sheng Jan
Results of Radiation Therapy for Regional Stage T4 Nasopharyngeal Carcinoma/ Chi-Yuan YehYuen-Liang LaiChang-Hung ChungKou-Hwa ChangYih-Cherng Lai
接受輻射治療之鼻咽腫瘤患者其視網膜病變之評估/ 張東杰林淵謙陳墩禄楊克仁陳麗惠湯國政
Postoperative Low Dose Single Fraction Irradiation for Prevention of Heterotopic Bone Formation after Hip Surgery/ Le-Jung WuSang-Hue YenTain-Hsiung ChenLing-Wei WangKwan-Hwa ChiKuang Y. Chen
Patterns of Pelvic Recurrence and Results of Salvage Treatment with Radiation Therapy for Recurrent Rectal Carcinoma/ Chong-Jong WangStephen Wan LeungHui-Chun ChenLi-Min SunFu-Min Fang
Postoperative Radiotherapy for Malignant Gliomas/ Shyh-An YehStephen Wan LeungLi-Min SunChong-Jong WangHuey-Jiun ChenFu-Min Fang
Study on Radiation Safety of High Dose Rate Multiple Cobalt-60 Sources Teletherapy Machine/ Sang-Hue YenYuh-Lin LeeLiung S. ChaoMax M. ChaoDavid HC PanKuang Y. Chen
The Role of Epstein-Barr Virus Infection and the Immunocompetence of Patients with Nasopharyngeal Cancer/ Kuan-Chih ChowKuang Y. Chen
如何使用模擬攝影機之擋影托盤(shadow tray)確認擋塊位置/ 何聖佑鄭秀成雷德
醫用直線加速器系統構造與保養作業簡介/ 李財福梁雲王重榮許順能黃置柔吳嘉明
西藏癌病與衛生醫療現況/ 顏上惠劉淑娟陳光耀
C型行為與癌的關係--癌症心理學書評--/ 陳光耀
 
   
 
   

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