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題名:組織間插植熱治療使用熱透導管系統之研究     (14點)
Study of Interstitial Hyperthermia Using a Thermofuse System
著者:顏上惠(Sang-Hue Yen) ;江俊霖(Wesley Chiang) ;趙良曉(Liung-Sheau Chao) ;李玉麟(Yue-Ling Lee) ;季匡華(Kwan-Hwa Chi) ;王曼肇(Mann-Tchao Wang) ;陳光耀(Kuang Y. Chen)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:組織間插植熱治療 ; 熱透導管 ; Interstitial hyperthermia ; Thermofuse
刊名:放射治療與腫瘤學
頁碼:179-185
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

旦旦: 以組織掃植方式, 籍一次於腫瘤的針管插植,可精確且足夠地給予放射治療及熱治療( h y p e r therm ia ) 兩種相輔相成的治療﹒ 提高局部治療率。J-:J.電述i皮或射頻( radiofre q uency ) 為熱源, 加iE 及測jE易受其物理性之干擾。本研究之目的乃在於研究以熱透式導管( t h e r m of u s e)熱治療儀使用組織插植溫度外佈的情形。 扭扭盟主主:使用熟透導管熱治療儀,王子5J IJ 於熱治療之假體,豬肉及活體豬,依三至五層面( p l a n e ) ,以積體式( vo l u m e ) 式插植針管, 每層面五根, 每根依1 0 , 1 2 ' 1 5 mm 間距共三組。以熱偶(thermocou•p ie ) 實;!!Ij掃植區內、外不同位置溫度之外佈及變化情形, 至于析並相互比較。 結果: 於假體、豬肉與活體豬皆可藉調整循環前之水溫, 使1 0 及1 2 m m 間E巨之掃植區內達到理想之治療有效溫度,於活體豬內1 5 m m 部份問距﹒ 掃植區內則未達熱治療理想的溫度。活體豬肉測iE顯示近血管區峻,溫度顯著下降1 . 4 ~ 2 . 0 •C ° 結論: 本研究顯示﹒ 使用熟透導管系統作組織間掃植熱治療, 能於腫瘤區坡藉針管之掃植及不受物理性因素條件干擾之測量, 精確地給予及實測有效治療溫度,其加熱與測;且之準確性為目前其他體外熱治療﹒ 所無法比綴。估計與放射治療合用可提昇療效, 對存活期長之質質瘤( s o l i d tumor) ,助鑫尤多。
Purpose: Using intersitia l implantati on, one needle implantation procedure provides for two complimentary tr eatment modalities of radiothera py and hypert hermia with adequate dose and tem pera ture distribution , subsequent ly improving the loca l control. Pr oblems of interfer ence of heat delivery and temperature measur ement exist when we use micr owave or radi ofrequency as the heati ng source . This study aims at invest igating the heat distributi on using interstit ial thermofuse system. Ma terial and Methods: Th ermofuse hyperthermia system was used to study on phantom , pork and alive pigs . Volume needle impla nt at ion with 3-5 planes . 5 needles per plane were implanted . They were devided into 3 gro ups with 10,12 and 15 mm needle spacing . Thermocouples were used to mea sure the temper ature distribution inside and outs ide implantation areas . The dat a were analyzed and compa red. Results: In the study of phantom , pork and alive pigs, the implantation volume cou ld ac hieve idea l and effective hyperthermia temper atures at 10, 12 mm spac ing through the adjustment of wat er temperature bef ore circulation. In alive pigs, wit h a 15 mm needle spacing , the implanted volume could not ach ieve idea l temperatures . The temper atures wer e significant ly decreased by 1.4 -2.0°C in the are as nea r the vesse ls. Conclusion: Th is study shows that int er st itial hyperthermia using thermofuse sys tem is able to precisely provide effect ive hyperthermia temperature without the inte rfe rence of physics parameters in the rrno -rneasure rnent in impl anted tum or areas . The accuracy of hea t deliver y and temperature mea surement is better than other external hyperthermia systems . We est imate that the comb inat ion with radi otherap y ca n improve the treatment effect of solid tumor s . It is expected more beneficial, espec ia lly for those solid tumors with relatively long surv iva ls.


    

本卷期目次
放射治療與腫瘤學
電子射束遮擋照野劑量輸出之研究/ 黃英明陳海雯郭珍妮王裕文
腔內射頻熱治療時假體內溫度分佈之研究/ 熊佩韋許文林蘇振隆張玉鈴蘇志中施榕平
不對稱準直儀在放射治療技術上之運用/ 劉明祥梁雲呂宗憲康暐篁吳嘉明
EB病毒與促癌物協同作用能誘發裸鼠體內人的鼻咽癌/ 曾毅劉振聲滕智平李寶民蘇玲紀志武劉彥仿
The Use Factor for Protective Barrier in a Medical Linear Accelerator Installation/ Pao-Shu ChangChih-Jen HuangShi-Long LianYu-Hui Ho
鼻咽癌病人使用一日兩次多分次照射之急慢性副作用分析/ 任益民許文林吳錦榕蘇志中熊佩韋張立平張東浩
組織間挿植熱治療使用熱透導管系統之研究/ 顏上惠江俊霖趙良曉李玉麟季匡華王曼肇陳光耀
維生素C對於KB及CHO細胞放射線敏感度之影響/ 許文林黃經民
Dual Involvement and Its Potential Significance of Epstein-Barr Virus and Human T Lymphotropic Virus Type I in Nasopharyngeal Carcinoma/ Koshi MaruyamaMotohiro MiyauchiShigenobu MochizukiNobuko KoshikawaKiyoko Kawamura
A Brief Report of Forty-Fourth Annual Meeting of the Radiation Research Society/ Ji-Hong HongSimon G. Tang
EB病毒與促癌物協同作用能誘發裸鼠體內人的鼻咽癌/ 曾毅劉振聲滕智平李寶民蘇玲紀志武劉彥仿
Dual Involvement and Its Potential Significance of Epstein-Barr Virus and Human T Lymphotropic Virus Type I in Nasopharyngeal Carcinoma/ Koshi MaruyamaMotohiro MiyauchiShigenobu MochizukiNobuko KoshikawaKiyoko Kawamura
鼻咽癌病人使用一日兩次多分次照射之急慢性副作用分析/ 任益民許文林吳錦榕蘇志中熊佩韋張立平張東浩
維生素C對於KB及CHO細胞放射線敏感度之影響/ 許文林黃經民
組織間插植熱治療使用熱透導管系統之研究/ 顏上惠江俊霖趙良曉李玉麟季匡華王曼肇陳光耀
腔內射頻熱治療時假體內溫度分佈之研究/ 熊佩韋許文林蘇振隆張玉鈴蘇志中施榕平
電子射束遮擋照野劑量輸出之研究/ 黃英明陳海雯郭珍妮王裕文
不對稱準直儀在放射治療技術上之運用/ 劉明祥梁雲呂宗憲康暐篁吳嘉明
The Use Factor for Protective Barrier in a Medical Linear Accelerator Installation/ Pao-Shu ChangChih-Jen HuangShi-Long LianYu-Hui Ho
A Brief Report of Forty-Fourth Annual Meeting of the Radiation Research Society/ Ji-Hong HongSimon G. Tang
 
   
 
   

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