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1
題名:第四期鼻咽癌的預後因子     (16點)
Prognostic Factors of Stage IV Nasopharyngeal Cancer
著者:劉文山(Wen-Shan Liu) ;張慶雄(Ching-Hsiung Chang) ;胡渝昌(Yu-Chang Hu) ;陳建勳(Chien-Hsun Chen) ;吳永平(Yung-Ping Wu) ;陳光耀(Kuang Y. Chen)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:鼻咽癌 ; 放射治療 ; 預後因子 ; Nasopharyngeal cancer ; Radiotherapy ; Prognostic factor
刊名:放射治療與腫瘤學
頁碼:1-8
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

目的﹒ 評估第四期鼻咽癌的治療成效與其預後因子。 材料與方法: 從1 9 9 1 年4 月至1 9 9 5 年6 月間, 高雄榮民總醫院共有的名可評估的Tl -4 N 2-3 M O 骨咽癌患者。所有的名患者都接受了治癒性的放射線治療;其中值劑量為72 0 0 cGy (鈍圍為6800至7670 c Gy ) 。本研究除計算治療後之存活率外, 亦分析了T 及N 期JjIJ與失敗型態的關係。可能影響預後的因子均先以單變異數方法分析;有意義的預後因子再以多變異數方法分析。 結果: 五年存活率、局部控制存活率與疾病控制存活率分別為4 3 . 7 昆、科研及4 0 . 3 克。以單變異教方法今析.本研究發現T期別、T4腰瘤侵犯特徵、總治療時間、淋巴結放療反應、TI N期別組合、性別及血小板等均為有意義之預後因子。以多變異數方法分析, 貝IJ只有T4腫瘤侵犯特徵會影響存活萃, TI N 期別組合會影響局部控制l存活率。 結論: 本研究發現第四期鼻咽癌患者的治療成果會隨不同預後因子而有所差異。以後在決定此期癌病的治療方針時, 可考慮依照不同的預後因子來規劃與設計不同的治療方式, ]:)提高治療成效。
Purpose: To evaluate the results and prognostic factors of Stage IV nasopharyngeal cancer. Methods and Materials : From April 1991 to June 1995,89 patients with Tl -4 N2-3MO nasopharyngeal cancer treated at the Veteran General Hospital-Kaohsiung were evaluated . All these patients had received definitive radiotherapy to a median dose of 7200 cGy (range from 6800 to 7670 cGy). The failure patterns according to different T and N stages were evaluated. The possible progno stic factor s were analysed by univariate analysis first , then those have significant p values were further eveluated by multi variate analysis. Results : The survival rate , local failure free survival and disease-free survival at 5 years were 43 .7%, 44.6% and 40.3%, respectively. The factor s including T stage , characteristics of T4 invasion , total treatment time , lymph node response rate, T and N grouping, sex and platelet counts all showed statistically significance by univariate analysis. The multi variate analysis revealed both the characteristics of T4 invasion and TIN grouping are significant to the overall survival and local failure free survival, respectively. Conclusion : This study disclosed that the patient s with Stage IV nasopharyngeal cancer have different prognosi s according to different factors. In the future, we might design treatment policies according to different prognostic factor s in an attempt to improve the treatment results.


    

本卷期目次
放射治療與腫瘤學
Estimation of Complication Probability for Non-Uniform Normal Tissue Irradiation Using the Effective Volume Method and Normal Distribution/ Mu-Tai LiuChi-Yuan YehJao-Perng LiuShing-Sheng HuangChung-Chi LeeYu-Ming LiuKuang-Y. Chen
晚期子宮內膜癌/ 吳孟浩張國華賴允亮王銘志
Evaluation of Major Salivary Gland Function by Sialoscintigraphy in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy/ Ping-Kun WengShyh-Ing GuanYee-Min Jen
Treatment Results of Hodgkin's Disease from 1977 to 1991 in National Taiwan University Hospital/ Louis Tak LuiChih-Chiech HsuNa-Na ChungPo-Ming WangChao-Yuan HuangLai-Lei Ting
早期子宮內膜癌的治療與預後因子/ 王銘志吳孟浩張國華賴允亮鍾昌宏劉岱瑋陳裕仁
放射手術與多照野放射治療早期復發性鼻咽癌之臨床病例報告/ 白冰清曾雁明劉千如李石增湯國政
動態式楔形濾板穿透因子之測量/ 黃英明郭珍妮陳海雯王裕文
Treatment Results of Oral Tongue Cancer/ Chao-Yuan HuangLouis Tak LuiPo-Ming WangNa-Na ChungLai-Lei Ting
全球資訊網(World Wide Web)上的放射治療Home Page:一年來的經驗與未來的展望/ 熊敬業梁雲陳翰森王重榮陳惠君孫立民方富民
第四期鼻咽癌的預後因子/ 劉文山張慶雄胡渝昌陳建勳吳永平陳光耀
Aggressive Combined Moddality in Inflammatory Breast Carcinoma with Minimal Distant Metastasis-A Case Report/ Robert TanAndrew YoungChing-Tang Wu
第四期鼻咽癌的預後因子/ 劉文山張慶雄胡渝昌陳建勳吳永平陳光耀
早期子宮內膜癌的治療與預後因子/ 王銘志吳孟浩張國華賴允亮鍾昌宏劉岱瑋陳裕仁
Treatment Results of Oral Tongue Cancer/ Chao-Yuan HuangLouis Tak LuiPo-Ming WangNa-Na ChungLai-Lei Ting
Treatment Results of Hodgkin's Disease from 1977 to 1991 in National Taiwan University Hospital/ Louis Tak LuiChih-Chiech HsuPo-Ming WangNa-Na ChungChao-Yuan HuangLai-Lei Ting
Estimation of Complication Probability for Non-Uniform Normal Tissue Irradiation Using the Effective Volume Method and Normal Distribution/ Mu-Tai LiuChi-Yuan YehJao-Perng LinShing-Sheng HuangChung-Chi LeeYu-Ming LiuKuang Y. Chen
動態式楔形濾板穿透因子之測量/ 黃英明郭珍妮陳海雯王裕文
晚期子宮內膜癌/ 吳孟浩張國華賴允亮王銘志
Evaluation of Major Salivary Gland Function by Sialoscintigraphy in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy/ Ping-Kun WengShyh-Ing GuanYee-Min Jen
放射手術與多照野放射治療早期復發性鼻咽癌之臨床病例報告/ 白冰清曾雁明劉千如李石增湯國政
Aggressive Combined Modality in Inflammatory Breast Carcinoma with Minimal Distant Metastasis-A Case Report/ Robert TanAndrew YoungChing-Tang Wu
全球資訊網(World Wide Web)上的放射治療Home Page:一年來的經驗與未來的展望/ 熊敬業梁雲陳翰森王重榮陳惠君孫立民方富民
 
   
 
   

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