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題名:鼻咽癌與治療前EB病毒VCA抗體指數的關係     (14點)
The Relationship between Pre-Treatment Nasopharyngeal Carcinoma and the Antibody Titers of Epstein-Barr Virus Capsid Antigen
著者:陳建勳(Chien-Hsun Chen) ;林立青(Lih-Ching Lin) ;胡渝昌(Yu-Chang Hu) ;劉文山(Wen-San Liu) ;張慶雄(Ching-Hsiung Chang)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:鼻咽癌 ; EB病毒 ; VCA抗體 ; 預後 ; Nasopharyngeal carcinoma ; EB virus ; Viral capsid antigen ; Prognosis
刊名:放射治療與腫瘤學
頁碼:101-107
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

目的: 探討放射線治療前臼病毒V C A 抗體指數和鼻咽宿患者臨床表徽的關係, 並分析抗體指數高低與預後的關f系。 材料及方法: 自1 9 9 1 年4 月至1 99 5 年9 月, 有10 1 位患者於治療前一個月內會接受凹病毒VCA抗體的測試。我們作抗體幾何平均指敏及血清陽性率對性別、年齡、W HO組織學形態和臨床至于湖等臨床因素關係的分析,並至于析鼻咽福之預後因子及凹病毒VCA t克體值與預後的關f系。 結果: 1 01 位愚者VCA 之l臥及I gG 抗體的幾何平均指數分別為102 及1 3 1 6 .而血清陽性率分別為87 .00 % 及9 1.7 0克。VCA-l gA 幾何平均指數在女性明顯較高(p=0 .0 40) • I趴血清陽性率則於年長及疾病期別高的思者有明顯偏高( p = 0 . 0 4 7 及。. 0 1 5 ) 。而V C A- l gG 抗骨童年日這些臨床表徵並無密切關係。日因癌預f車和性5] IJ 及疾病期別有關。而VC A 抗體陽性與否和抗體高低皆與預f是無關。 結論:雖然治療前的VCA抗體幾何平絢指數有隨期別增加而增加的趨勢﹒但無明顯差異。而V C Al叭血清陽性率和年齡、T 期別及削凶手于期有相關性。此外, VCA 抗體健並不可作為推測預後的因素。
Purpo se: To assess the relations hip betwee n the pre-Rff EBV VCA titers and the charac teristics of the patients with NPC and to analyze the prognostic value of the titers Materials alld Methods: From Apri l 199 1 to September 1995, 101 patients with nasopharyngeal carcinoma who received the examination of EBV VCA titers before radiotherapy were reviewed. We analy zed the corre lation between titers and clinical characteristics. including genders. age. WHO histologi c types and stages. We also tried to find the role of these titers in predicting prognosis. Results:We found that the geometric mean titers of EBV VCA-IgA and IgG of these 10I patients were 102 and 11 36 and the sero positive rates were 87% and 91.7%, respectively. The GMTs of IgA and IgG trended to be increased in advanced stages , but no significant difference in statistics. There is no significant difference of GMTs in other clinical features. except IgA titer in sex. The seropositive rates were higher in elders, higher T stage and adva nced stage. The role in pred icting prognosis was not found . Con clusions: The pre-treatment EBV VCA GMTs increase d in adva nced stages , but the difference was not significant a n~ they were not proper facto rs in predicting prognosis.


    

本卷期目次
放射治療與腫瘤學
硫酸亞鐵膠體劑量計在放射治療應用之原理與探討/ 羅濟慶李俊信
組織挿植式微波天線陣列熱療系統之假體研究/ 熊佩韋許文林蘇振隆紀瑞峻施榕平
Treatment Results of Malignant Lymphoma of Nasopharynx at National Taiwan University Hospital/ Louis Tak LuiWei-Chung HsuNa-Na ChungPo-Ming WangLai-Lei TingRuey-Long Hong
Leipzig Applicators之劑量特性/ 黃英明郭珍妮陳海雯王裕文
病毒檢驗在腫瘤診斷與治療上的應用/ 周寬基張錦霞周絢蘭曾文瑟陳光耀
鼻咽癌與治療前EB病毒VCA抗體指數的關係/ 陳建勳林立青胡渝昌劉文山張慶雄
Radiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and NeckRadiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and Neck/ Chung-Shuh KaoJian-Sheng JanChing-ilsiung ChangJin-Ching LinHsien-Chun TsengYih-Chyang Weng
婦女腹股淋巴結之放射治療技術/ 張東杰陳麗惠李紳豪湯國政
Endocrine Dysfunction in Patients with Nasopharyngeal Carcinoma after Radiotherapy -A Prospective Study with 10 Years Follow-Up/ Chun-Chieh WangJoseph T. ChangJen-Der LinSimon G. TangJi-Hong Hong
晚期鼻咽癌同步化學放射治療之研究-臺中榮總之經驗/ 林進清詹建勝曾顯群翁益強高忠恕王麗鈴
鼻咽癌與治療前EB病毒VCA抗體指數的關係/ 陳建勳林立青胡渝昌劉文山張慶雄
Postoperative Radiotherapy for Malignant Parotid Gland Tumors/ Li-Ly WangJian-Sheng JanJih-Ching LinHsien-Chun TsengYih-Chyang WengChung-Shuh Kao
Postoperative Radiotherapy for Malignant Parotid Gland Tumors/ 王麗鈴詹建勝林進清曾顯群翁忠恕高忠恕
Endocrine Dysfunction in Patients with Nasopharyngeal Carcinoma after Radiotherapy-A Prospective Study with 10 Years Follow-Up/ Chun-Chieh WangJoseph T. ChangJen-Der LinSimon G. TangJi-Hong Hong
婦女腹股淋巴結之放射治療技術/ 張東杰陳麗惠李紳豪湯國政
Leipzig Applicators之劑量特性/ 黃英明郭珍妮陳海雯王裕文
硫酸亞鐵膠體劑量計在放射治療應用之原理與探討/ 羅濟慶李俊信
組織插植式微波天線陣列熱療系統之假體研究/ 熊佩韋許文林蘇振隆紀瑞峻施榕平
病毒檢驗在腫瘤診斷與治療上的應用/ 周寬基張錦霞周絢蘭曾文瑟陳光耀
Radiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and Neck/ Chung-Shuh KaoJian-Sheng JanChing-Hsiung ChangJin-Ching LinHsien-Chun TsengYih-Chyang Weng
Treatment Results of Malignant Lymphoma of Nasopharynx at National Taiwan University Hospital/ Louis Tak LuiWei-Chung HsuNa-Na ChungPo-Ming WangLai-Lei TingRuey-Long Hong
晚期鼻咽癌同步化學放射治療之研究--臺中榮總之經驗/ 林進清唐建勝曾顯群翁益強高忠恕王麗鈴
 
   
 
   

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