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題名:組織插植式微波天線陣列熱療系統之假體研究     (14點)
The Phantom Study of Interstitial Microwave Antenna Array Hyperthermia System
著者:熊佩韋(Pei-Wei Shueng) ;許文林(Wen-Lin Hsu) ;蘇振隆(Jenn-Long Su) ;紀瑞峻(Ruey-Jiun Jih) ;施榕平(Rom-Ping Shih)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:微波天線陣列 ; 溫度分佈 ; 假體 ; 穩態 ; 水流流速 ; Microwave antenna array ; Temperature distribution ; Phantom ; Steady state ; Flow rate
刊名:放射治療與腫瘤學
頁碼:147-153
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

目的: 在揉討使用組織掃植式微波熱療系統於假體內i旦度至于佈之狀況, 以評估該系統之發展。 材料與方法: 本研究乃採周一種新設計的微波天線套管式向軸狹縫天線來做為實駿中的加熱源,並利用六根天線所組成的天線陣子Ij ﹒ 以期能於陣列所涵蓋之鈍圍內作區域性2日熟。假體的實駿分兩部今完成,第一部份在不考慮‘血液循環對於溫度分佈所產生的影響下﹒利用組織掃植式微波熱治療系統先針對人體均質假體進行加熱。為了能夠測得假體中不同深度的溫度分佈情形,因此於加熱一段時間且假錯之溫度至于佈到達1憲態後, 即開始以每次5 mm 的距離調整溫度計插入之深度,以fjb則多個深度平面的溫度分佈結果。第二部份,貝IJ利用相同的熱治療系統並配合自行設計的模綴血液循環系統,對肌肉假體進行加熱試驗﹒ 與第一部份不同的是另加一水管貫穿肌肉假髓的中心位置,藉水溫3 6 "c 的循環,夜流過以模綴血,夜流動狀態, 並分別以至1童不同水流速度( 2 5 、5 0 、75 、100 和125 m l! m in) 來討論其溫度外佈狀態。 結果: 第一部份的.. 駿結果顯示此一天線陣列車時在時在天線方向上所產生的溫度分佈情形, 其最高溫度是出現於接近天線前端之狹縫區域﹒ 同時在天線頂端處亦能達到有效的治療溫度的℃ 。第二部份研究則顯示在有水流的狀態下,其溫度上升之斜率明顯低於無水流的狀態, 因而證賣血流對於假體在加熟時其能量的吸岐確實有所影響, 而且隨著水流流遠的增大, 其影響亦呈現還漸增加的趨勢, 但是當水流流速到達一定程度時(1 0 0 ml/min ) . 水流對於能量之影響將呈現一種定狀態﹒ 此時假體的能量流失率不再隨著水流流速的增加而增加。 結論: 在本系統溫度監控軟體的自動控制下, 對於目前考慮. 血流的假體實驗設計而言, 利用此一熱療系統來進行加熟, 將可使整個天線陳列所圍成的區域其溫度至于佈維持於4 3-4 5 "c ﹒ 而此一實蛤結果將有助於未來動物質鍾的權展。
Purpose: To test the performance of interstitial microwave antenna array hyperthermia system using a phantom model with or without flow effect. Material and Method: The heating devi ce was a custom-made interstitial microwa ve antenna array hyperthermia system. Six 2450-M Hz antennas which were implanted on the corners of a hexagon with intercather spacing of 15 mm were used in this system. A phantom with flow was designed, namely, one silicone tube inserted into a homogenous muscle phantom. The temperature data from four fibroo ptic thermometers were fed to the personal computer which could record and analyze the data, also could contro l the output power of microwave source. To test the system performance, we devided the study into two stages . In the first stage, the thermal distribution in a phantom without flow was conducted. In the second stage, the experiments in a phantom with different flow rates (25. 50. 75. 100 and 125 ml/min) were designed. The flow rates of water through silicone tubes were controlled by a microtube pump. Result : Using the automatic temperature and power control in this interstitial microwave antenna array hyperthermia system, the temperature distribution in phantom can be maintained uniformly in the range of 43-45 "C. The first-stage study showed that there was a tendency that the temperature was concentrated around the antennas. For the flow effect on thermal distr ibution, the results demon strated that the faster flow rate would take more energy away in the transient period . However. the rate of energy loss caused by flowing water became cons tant when the flow rate was faste r than 100ml/min. Conclusions: An inters titia l microwave antenna array hyperthe rmia system for deep-seated heating was deve loped. The superior ability of this system in maintaining uniform temperature distribu tion around the heating area was also clearly demonstrated.


    

本卷期目次
放射治療與腫瘤學
硫酸亞鐵膠體劑量計在放射治療應用之原理與探討/ 羅濟慶李俊信
婦女腹股淋巴結之放射治療技術/ 張東杰陳麗惠李紳豪湯國政
Leipzig Applicators之劑量特性/ 黃英明郭珍妮陳海雯王裕文
Endocrine Dysfunction in Patients with Nasopharyngeal Carcinoma after Radiotherapy -A Prospective Study with 10 Years Follow-Up/ Chun-Chieh WangJoseph T. ChangJen-Der LinSimon G. TangJi-Hong Hong
晚期鼻咽癌同步化學放射治療之研究-臺中榮總之經驗/ 林進清詹建勝曾顯群翁益強高忠恕王麗鈴
Treatment Results of Malignant Lymphoma of Nasopharynx at National Taiwan University Hospital/ Louis Tak LuiWei-Chung HsuNa-Na ChungPo-Ming WangLai-Lei TingRuey-Long Hong
病毒檢驗在腫瘤診斷與治療上的應用/ 周寬基張錦霞周絢蘭曾文瑟陳光耀
組織挿植式微波天線陣列熱療系統之假體研究/ 熊佩韋許文林蘇振隆紀瑞峻施榕平
鼻咽癌與治療前EB病毒VCA抗體指數的關係/ 陳建勳林立青胡渝昌劉文山張慶雄
Radiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and NeckRadiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and Neck/ Chung-Shuh KaoJian-Sheng JanChing-ilsiung ChangJin-Ching LinHsien-Chun TsengYih-Chyang Weng
鼻咽癌與治療前EB病毒VCA抗體指數的關係/ 陳建勳林立青胡渝昌劉文山張慶雄
Postoperative Radiotherapy for Malignant Parotid Gland Tumors/ Li-Ly WangJian-Sheng JanJih-Ching LinHsien-Chun TsengYih-Chyang WengChung-Shuh Kao
Postoperative Radiotherapy for Malignant Parotid Gland Tumors/ 王麗鈴詹建勝林進清曾顯群翁忠恕高忠恕
Endocrine Dysfunction in Patients with Nasopharyngeal Carcinoma after Radiotherapy-A Prospective Study with 10 Years Follow-Up/ Chun-Chieh WangJoseph T. ChangJen-Der LinSimon G. TangJi-Hong Hong
婦女腹股淋巴結之放射治療技術/ 張東杰陳麗惠李紳豪湯國政
Leipzig Applicators之劑量特性/ 黃英明郭珍妮陳海雯王裕文
硫酸亞鐵膠體劑量計在放射治療應用之原理與探討/ 羅濟慶李俊信
組織插植式微波天線陣列熱療系統之假體研究/ 熊佩韋許文林蘇振隆紀瑞峻施榕平
病毒檢驗在腫瘤診斷與治療上的應用/ 周寬基張錦霞周絢蘭曾文瑟陳光耀
Radiation Therapy in Extranodal Non-Hodgkin's Lymphoma of the Head and Neck/ Chung-Shuh KaoJian-Sheng JanChing-Hsiung ChangJin-Ching LinHsien-Chun TsengYih-Chyang Weng
Treatment Results of Malignant Lymphoma of Nasopharynx at National Taiwan University Hospital/ Louis Tak LuiWei-Chung HsuNa-Na ChungPo-Ming WangLai-Lei TingRuey-Long Hong
晚期鼻咽癌同步化學放射治療之研究--臺中榮總之經驗/ 林進清唐建勝曾顯群翁益強高忠恕王麗鈴
 
   
 
   

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