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1
題名:全身皮膚電子束放射治療之劑量學     (20點)
Dosimetry for Total Skin Electron Beam Radiation Therapy
著者:謝忠志(Chung-Ching Hsieh) ;戴宏旗(Hung-Chi Tai) ;陳弘政(Hung-Cheng Chen) ;奚正義(Cheng-I His) ;張國華(Kou-Haw Chang) ;賴允亮(Yuen-Liang Lai) ;吳孟浩(Meng-Hao Wu)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:全身皮膚電子束放射治療 ; 六對照野法 ; 劑量學 ; Total skin electron radiation therapy(TSET) ; Six- dual-fie ld technique ; Dosimetry
刊名:放射治療與腫瘤學
頁碼:35-44
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

且且: 描述本科考量客觀設備條件, 參酌「六對照野法J 進行全身皮膚電子束放射治療之劑量學務經駿。 拉起盟主主主﹒ 射源至表面距離( SS D ) 是3 2 3 cm '並在治療平面前1 5 cm處架設- 0.8 c m 厚度之壓克力板以發散射來並衰減初能量為6 MeV 的電子能量。首先測定能使垂直方向達到最佳劑量均勻度的成對照野角( dual-field angle) , 並量測水平和垂直方向的照野平坦度。接著利用X 光片劑量法求出電子在治療平面的劑量分佈及相關數據,據以校正直線加速器的o u t p u t 。再利用熱發光劑量計(TLD) 測量人形假體上以六個d u a l -fi e l d s 和一個d u a l -fi e l d 照射的吸收費l 量之比值以決定倍數因子( multiplication fa ctor ﹒ 簡稱M F) , 便可求得治療每單一照野所必須給子的劑量。再完全模綴實際治療條件,以TLD進行i n vivo dosimetry ,確認病人體表劑量並評估各點的劑量差異( dose varia tion) 。 益基: 我們所實驗或測量得到的d u e l-fi e l d angle (20 ') 和m ultiplica tion factor ( 2 .68) 等參數﹒ 與他人經驗相符。電子的劑量分佈及X-ray background (0 .7 5 %) 亦令人滿意。直線加速器的outp ut 雖大幅減小( 0 . 0 6 8 4 cGy/ MU) ,但藉著提高劑量率( 600 MU/mi n )使每次治療時間不致過長。病人體表的dose va r i a t i o n 大致與文獻報告相符合。惟水平方向的照野平坦度略為不足( 6 0 c m 的鈍園內是±10% ) 。 益益:全身皮膚電子束放射治療的技術極繁複﹒ 對每位病人的劑量學考慮須兼顧個別性、系統性與完整性。
Purpose: Dependent on the equipment and facilities available, we adopted "six -dual -field technique" to administer total skin electron radiation therapy (TSET) . Our exp er ience with dosimetric measurement s for this modality is reported . Materials and Methods: The source-to-surface distan ce (SSD) was extended to be 323 cm, and an 0.8 em-thick acrylic screen was installed at 15 cm in front of the treatment plan e to scatte r the beam and attenuate the elec tron energy. At first, the optimal dual- field angle was determ ined in orde r to achieve feas ible dose uni formity in the vertical dimen sion. and then fie ld flatn ess co uld be ass ured. Film dosimetry was applied to define depth dose distribution profil e of electron beam at treatm ent plan e. Accordingly, the output of the linear accelerator could be ca librated. Multiplication factor was determined to be 2.68 , repres ented as the ratio of the absorbed dose from all six dual-fields to that from one dual -field measured with thermoluminescent dosimeters (TLDs) taped at a Rando phantom. Thus, the value of MU for each field could be ca lculated. TLDs were used for in vivo dosimetry to verify the skin dose and eva luate dose variatio n at different anatomic sites. Results : The determined dual -field angle (20°) and multiplica tio n fac tor (2 .68) were comparable to tho se describ ed in the literature. Depth dose distribution and beam penetr ation were satisfy ing, and Xray background level (0.75%) was also acceptable. Markedl y decreased output of the Linac (0.0684 cGy/MU) could be partially compensated with the esc alation of dose rate (600 MU/min ). Thu s, each treatment would not cost too much time. Does variation among different sites at skin is compatible with the ex perience of other institutions . Instead, field flatn ess in the horizontal dimension (± I0% within 60 em) did not meet the requirement given by AAPM. Conelusion : The technique of TSET is complex. Dosimetry for this modality should be studied case by case sys tematically and thorou ghl y.


    

本卷期目次
放射治療與腫瘤學
成人軟組織肉瘤病人之術後輔助性放射治療/ 簡君儒陳尚文謝長堯黃昭源林芳仁
全身照射治療的劑量測定與兩側平行對照技術的應用/ 吳簡坤林盈釧郭祥吉吳東和黃英強陳志成蔡玉真成佳憲簡哲民
放射線照射及BSO處理後多形性神經膠母瘤細胞內麩氨基硫含量變化之研究/ 黃經民黃旭山許文林熊佩韋李偉華
Hodgkin's Disease, Changing Pattern of Histology Subgroup and AGE Distribution, VGH-Taipei's Experience with 240 Cases over 26 Years--1970 to 1995/ Chung-Yih WangJing-Yi ChaoShan-Huei Yen
Effect of Lomustine on N-Acetyltransferase Activity in RAT Glioma in Vitro Cultured Cells/ Chih-Chung SuMiki KiyokawaJen-LiaoChi-Wen KaoMing-Tsuen HsiehJin-Gung ChungChi-Fu Hung
全身皮膚電子束放射治療之劑量學/ 謝忠志戴宏旗陳弘政奚正義張國華賴允亮吳孟浩
根據TG-51議定書以不同游離腔量測直線加速器電子輸出劑量之比較/ 林招膨林桂華朱鐵吉劉幕台黃勝賢張雅婷黃昭源
臨床劑量測定方法的最新發展-TG-51議定書/ 鄭秀成李俊信陳君德曾鑠鑠雷德張幗孫
放射線照射及BSO處理後多形性神經膠母瘤細胞內麩氨基硫含量變化之研究/ 黃經民黃旭山許文林熊佩韋李偉華
成人軟組織肉瘤病人之術後輔助性放射治療/ 簡君儒陳尚文謝長堯黃昭源林芳仁
Hodgkin's Disease, Changing Pattern of Histology Subgroup and Age Distribution, VGH-Taipei's Experience with 240 Cases Over 26 Years-1970 to 1995/ Chung-Yih WangJing-Yi ChaoShan-Huei Yen
全身照射治療的劑量測定與兩側平行對照技術的應用/ 吳簡坤林盈釧郭祥吉吳東和黃英強蔡玉真成佳憲簡哲民
全身皮膚電子束放射治療之劑量學/ 謝忠志戴宏旗陳弘政奚正義張國華賴允亮吳孟浩
臨床劑量測定方法的最新發展--TG-51議定書/ 鄭秀成李俊信陳君德曾鑠鑠雷德張幗孫
根據TG-51議定書以不同游離腔量測直線加速器電子輸出劑量之比較/ 林招膨林桂華朱鐵吉劉幕台黃勝賢張雅婷黃昭源
Effect of Lomustine on N-Acetyltransferase Activity in Rat Glioma in Vitro Cultured Cells/ Chih-Chung SuMiki KiyokawaJen LiaoChi-Wen KaoMing-Tsuen HsiehJin-Gung ChungChi-Fu Hung
 
   
 
   

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