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1
題名:臨床劑量測定方法的最新發展--TG-51議定書     (44點)
The Latest Development in Clinical Dosimetric Methodology-Aapm's Tg-51 Protocol
著者:鄭秀成(Shiu-Chen Jeng) ;李俊信(Jason J. S. Lee) ;陳君德(Jiun-Der Chern) ;曾鑠鑠(Soso Tseng) ;雷德(Louis T. Lui) ;張幗孫(Ngot-Swan Chong)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:認證通過劑量校正的實驗室 ; 阻擋本領比值 ; 水中吸收劑量校正因子 ; Accredited Dosimetry Calibration Laboratory ; Stopping power ratios ; Absorbed-dose-to-water calibration factors
刊名:放射治療與腫瘤學
頁碼:45-66
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

旦且: 本文首先介紹T G引議定害的內容, 檢討歷年來臨床劑量測量方法的演進, 並且分別依照TG -2 1 、T G - 5 1 議定書的方法量測高能直線加速結﹒ 比較輸出劑量值的改變, 最後提出更新劑量測量方法時應該審慎考量的事1頁,避免造成臨床的街擊。 坐起盟主法使用認證通過的劑量校正實驗室( Acc red ited Dosimetry Calibration Laboratory , ADC L ) 校正的測量器材, Keithley 35 6 17 E8 5 電量計, 配合N E257 1 0 . 6c . c .是夫型圓柱式游離腔、何W N233430 . 04c . c 平行板式游離腔, 對Va ri a n 高能直線加速器C li n i c 6j 100 (光子能量為6 MV ) 與Clini c1800 (光子能量為6、1 8帥,電子能量為6 、9 、1 2、1 6 、2 0 M eV ) 量測輸出劑量, 分別依照TG-21 、TG-51 議定害的方法測量高健直線加速器的輸出劑量, J..:J,比較每監視單位的吸收劑量( c Gyj M U )變化情況。 益基: 在6 MV 光子的變化量分別為0 .7昆、1.4克, 18 M V 光子的變化量為2 . 2% '平均為1. 43 % '能量越高變化量越大, 可能由於能譜分布較廣, 且高能光子有較大的散射,使得TG♂ l與羽毛l在估算輸出劑量之結果有較大的差別;電子的變化量在1. 5 - 2 . 2%之間,對能量的改變並沒有明顯的趨勢, 平均的變化量為1. 84% '較光子略高, 可能原因為TG引議定書在電子射來劑量量測方面, 由於測量位置與T G- 2 1 議定書不同, 而且使用較準確的過程來描述實際臨床的電子射東與阻擋本領比值的關係,並將使用平行板游離腔納入評估,使得電子射來在劑量測量時,會有稍微大一點的改變。 益益:由於TG - 5 1 議定書不需要使用阻擋本領比值( stopping-power r ati o s ) 與質量能量吸收係數( mass-energyabsorption coefficie nts) 等龐大、繁瑣的表格, 使用者也不需要計算任何理論上的劑量因子,使得T Gδ l議定書在觀念上或使用上都較T G♂ l議定書單純、容易許多,誤差也相對地降低,更為工作方便, 將測量過程簡要地歸納成工作單( worksheets ) ,使用者只要依循著工作單的步驟,就可以很簡單地將劑量準確地測暈出來。為降低臨床劑量測定時所有可能的誤差,並符合日益精進的治療技術與劑量準確度的要求,在此籲請國家原級標準實驗室廣泛提供游離腔的水中吸收劑量校正因子( a bso巾ed-dose-t
Purpose: This art icle introduces and compares the latest TG-51 clini cal dosimetry protocol to the earlier protocol. TG-2 1. Based on the methodology of TG-21 and TG-51. the differences in clinical dosimetry measurements for both protocols are described and performed. Finall y. preca ution s in performing the latest protocol were listed to avoid errors in cli nic. Materials and Methods: The electro meter (Keithley 356 17EBS) with 0.6 c.c. Farmer type cylindrical ion chamber (NE257 1) and 0.04 c.c. plane parallel ion chambe r were employed for the measurements. The elec tromete r and ion chambers were authe nticated by the Accredited Dosimet ry Ca librat ion Laborat ory (ADCL) in University of Texas. Varian linear accelerators Ciinic6/100 sin: 358 ( Photon beam energy with 6 MV ) and Cli nic 1800 sin: 180 ( Photon beam energies with 6 and 18 MV, electron beam with energies 6, 9. 12. 16 and 20 MeV ) were used for output measurements. The measurement protocols were based on TG-21 and TG-51 respective ly. with output doses obtained to observe the variations in the monitor unit of the absorbed dose (cGy/MU). Results: The variations of monitor unit in 6 MV photon were within 0.7% and 1.4%. 18 MV photon was 2.2%. and the ave rage for photon energies was 1.43%. The higher the photon energy. the larger the variation. suggesting that higher photon energies produce more scatter radiation due to wider distributed ene rgy spectrum. For the electron beam. the varia tions in monitor units were within 1.5 - 2.2% with the average of 1.84%, showing no dependency with the electron beam energ ies. The variations in electron beam output were slightly higher than the photon beam , possible reasons are the measurement point s in TG-5 1 protocol for electron beam is different from earlier protocol, a more precise method to prescribe the relationshi p between the clinical beam qua lity and stopp ing power ratio of the electron beam and the plane parall el ion chamber is cons idered for the electron beam measurements. Conclusion: The TG-51 protocol is simple compared to TG-21 protocol as large tables of stopping power ratios and mass-energy absorption coefficients are omitted and the user does not need to calculate any theoret ical dosimetry facto rs. hence reduces calc ulation errors. For convenie nce. worksheets encompass the measurement steps and requi red equipment is provided. In Taiwa n. it is strongly recommended that national primary standards laboratory should be established to provide the absorbed-do seto- water calibration factor ( N7}~:') for ion chambers to avoid clin ical erro rs and to meet the accuracy in adva nced radiatio n therapy and dosimetry.


    

本卷期目次
放射治療與腫瘤學
Effect of Lomustine on N-Acetyltransferase Activity in RAT Glioma in Vitro Cultured Cells/ Chih-Chung SuMiki KiyokawaJen-LiaoChi-Wen KaoMing-Tsuen HsiehJin-Gung ChungChi-Fu Hung
根據TG-51議定書以不同游離腔量測直線加速器電子輸出劑量之比較/ 林招膨林桂華朱鐵吉劉幕台黃勝賢張雅婷黃昭源
放射線照射及BSO處理後多形性神經膠母瘤細胞內麩氨基硫含量變化之研究/ 黃經民黃旭山許文林熊佩韋李偉華
臨床劑量測定方法的最新發展-TG-51議定書/ 鄭秀成李俊信陳君德曾鑠鑠雷德張幗孫
全身皮膚電子束放射治療之劑量學/ 謝忠志戴宏旗陳弘政奚正義張國華賴允亮吳孟浩
全身照射治療的劑量測定與兩側平行對照技術的應用/ 吳簡坤林盈釧郭祥吉吳東和黃英強陳志成蔡玉真成佳憲簡哲民
Hodgkin's Disease, Changing Pattern of Histology Subgroup and AGE Distribution, VGH-Taipei's Experience with 240 Cases over 26 Years--1970 to 1995/ Chung-Yih WangJing-Yi ChaoShan-Huei Yen
成人軟組織肉瘤病人之術後輔助性放射治療/ 簡君儒陳尚文謝長堯黃昭源林芳仁
放射線照射及BSO處理後多形性神經膠母瘤細胞內麩氨基硫含量變化之研究/ 黃經民黃旭山許文林熊佩韋李偉華
成人軟組織肉瘤病人之術後輔助性放射治療/ 簡君儒陳尚文謝長堯黃昭源林芳仁
Hodgkin's Disease, Changing Pattern of Histology Subgroup and Age Distribution, VGH-Taipei's Experience with 240 Cases Over 26 Years-1970 to 1995/ Chung-Yih WangJing-Yi ChaoShan-Huei Yen
全身照射治療的劑量測定與兩側平行對照技術的應用/ 吳簡坤林盈釧郭祥吉吳東和黃英強蔡玉真成佳憲簡哲民
全身皮膚電子束放射治療之劑量學/ 謝忠志戴宏旗陳弘政奚正義張國華賴允亮吳孟浩
臨床劑量測定方法的最新發展--TG-51議定書/ 鄭秀成李俊信陳君德曾鑠鑠雷德張幗孫
根據TG-51議定書以不同游離腔量測直線加速器電子輸出劑量之比較/ 林招膨林桂華朱鐵吉劉幕台黃勝賢張雅婷黃昭源
Effect of Lomustine on N-Acetyltransferase Activity in Rat Glioma in Vitro Cultured Cells/ Chih-Chung SuMiki KiyokawaJen LiaoChi-Wen KaoMing-Tsuen HsiehJin-Gung ChungChi-Fu Hung
 
   
 
   

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