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題名:ANALYSIS ON THE VARIATION OF RESPIRATORY ORGAN MOTION AND A PRELIMINARY FEASIBILITY STUDY FOR A VOICE COACHING TECHNIQUE TO IMPROVE THE REPRODUCIBILITY OF RESPIRATORY CYCLE BETWEEN TREATMENTS     (24點)
呼吸器官運動之變異性分析及呼吸導引技術之可行性研究
著者:James C. Li(李必忍) ;Wen-Shan Liu(劉文山) ;Hsiang-Chi Kuo(郭祥吉) ;Li-Miao Chen(陳理妙) ;David Huang(黃英強) ;Chi-Wei Hsu(徐啟偉) ;His-Chang Chang(張席昌)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:治療中 ; 治療間 ; 呼吸器官運動 ; Intrafraction ; Interfraction ; Respiratory organ motion
刊名:Therapeutic Radiology and Oncology
頁碼:1-12
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

且且: 放射治療的進步允許腫瘤劑量的提昇, 從而促進更高的腫瘤控制率, 然而其複雜性也需相對的嚴格控制器官連動造成之不確定度。器官運動造成之不確定度主要可分為( 一) 體內器官運動形成電腦斷層影像之假影; ( 二)器官運動影響治療中之劑量分布; ( 三) 器官運動影響分次治療間之劑量。對橫隔膜上下之腫瘤, 呼吸是影響體內器官運動之主要因素。為了進一步瞭解呼吸造成器官運動之大小, 本文探討( 一)自由呼吸與閉氣呼吸腫瘤與重要器官之形狀大小差異; ( 二)呼吸器官在頭尾方向之位移大小; ( 三) 研究以呼吸導引技術改善治療間呼吸週期與器官運動之變異。 材料自台注: 本實驗資料來源為西元2 0 0 1 年3 月至1 0 月間於本院從事胸腹部放射治療之病患,使用材料與方法包括螺旋式電腦斷層掃瞄機各取兩組影像及運用立即式呼吸同步透視影像觀察體內器官運動。 結果與討論: 本分析顯示自由呼吸影像與閉氣影像差別甚大。橫隔膜在頭尾方向之位移可達15.5 ± 3.5 lUlU ' 膜臟則有1 3 . 7 ± 2.4 lUlU 0 本實驗顯示呼吸導引技術可改善某些呼吸不穩定患者之呼吸週期,從而能有效的尋求進一步控制其體內呼吸器官運動, 至於某些病患其呼吸原本即以規律者,呼吸導引對其反而不利。
Purpose : New advances in radiotherapy technology enable us to attain higher dose delivery to tumor region, resulting in greater tumor control probability, with this sophistication there is more demand to control the uncertainties contributed by organ motion. The organ motion related uncertainties can be mainly classified into three main categories: (i) the blurring of planning images due to internal organ motion during CT scan acquisition; (ii) intrafractional organ motion that affect the dose distribution within a single treatment delivery; (iii) interfractional organ motion that affect the dose distribution between treatments. For patients with supradiagphragmatic and infradiagphragmatic tumor, respiration is a major factor that causes the displacement of the internal organ. For further understanding the magnitude of the respiratory organ motion, we endeavor to investigate: (i) the geometrical differences in spatial displacement of the tumor and critical organ while in free breathing status and breath holding status; (ii) measures the magnitude of the respiratory organ motion in the cranio-caudal direction; (iii) makes a preliminary feasibility study of the coaching breathing technique to improve the reproducibility of the respiratory cycle and hence reduce the variation of organ motion in between treatment. Materials and Methods : The data were collected between March 2001 to October 2001 in our department from subjects undergoing radiation therapy of the thoracic and abdominal regions using our spiral CT and real time Respiratory Gating system to measure and analyze the variation of respiratory organ motion. A voice coaching technique is designed to improve the consistency of the respiration cycles. Results and Conclusions : Our analysis shows a significant variation of tumor and organ geometry between free breathing and breath holding state. The cranio-caudal displacement are 15.5 ± 3.5 mm for diaphragm and 13.7 ± 2.4 mm for pancreas, respectively. For patients in our study, coaching technique may improve the reproducibility for those patient whose breathing cycles is not consistent within intrafraction treatment, but not for those with consistent cycles.


    

本卷期目次
Therapeutic Radiology and Oncology
胸部固定器設計與臨床上之應用/ 呂宗憲蕭世禎吳錦榕阮昭銘朱慶文葉如娦彭秋萍游佩潔
子宮頸癌術後放射線治療病人組織病理學預後因子之多變數分析/ 賴耿光馬玉麟許瑞昌葉坤土賴義雄林隆堯周明智
Post-Operative Combination of Radiotherapy and Chemotherapy in Esophageal Cancer/ Chien-Hsun ChenChing-Hsiung ChangYu-Chang HuChung-Man LeungKuo-Chen Chang
Rarely Reported Liver Toxicity in Patients Who Were Hepatitis B Carrier and Underwent Chemoirradiation for Gastric Cancer/ Chao-Ming HuangJason Chia-Hsien ChengStella Y. TsaiMei-Ching LiuYih-Lin ChungSkye Hon-Giun ChengWei-Tse FangPo-Sheng YangJames Jer-Min JianAndrew T. Huang
Analysis on the Variation of Respiratory organ motion and a Preliminary Feasibility Study for a Voice Coaching Technique to Improve the Reproducibility of Respiratory Cycle between Tteatiments/ James C. LiWen-Shan LiuHsiang-Chi KuoLi-Miao ChenDavid HuangChi-Wei HsuHis-Chang Chang
A Dosimetric Comparison of the Predictive Value of Two Rectal Reference Points for Late Rectal Complications Following the Treatment of Cervical Cancer by High-Dose-Rate Brachytherapy/ Shang-Wen ChenJi-An LiangShih-Neng YangHui-Ling KoCheng-Pang TuAn-Cheng ShiauFang-Jen Lin
電腦斷層模擬攝影應用於全腦脊椎照射照野之設計與評估/ 曾雁明陳臣苑陳汶城林俊彥姚學華李紳豪曾振淦
ANALYSIS ON THE VARIATION OF RESPIRATORY ORGAN MOTION AND A PRELIMINARY FEASIBILITY STUDY FOR A VOICE COACHING TECHNIQUE TO IMPROVE THE REPRODUCIBILITY OF RESPIRATORY CYCLE BETWEEN TREATMENTS/ James C. LiWen-Shan LiuHsiang-Chi KuoLi-Miao ChenDavid HuangChi-Wei HsuHis-Chang Chang
POST-OPERATIVE COMBINATION OF RADIOTHERAPY AND CHEMOTHERAPY IN ESOPHAGEAL CANCER/ Chien-Hsun ChenChing-Hsiung ChangYu-Chang HuChung-Man LeungKuo-Chen Chang
電腦斷層模擬攝影應用於全腦脊椎照射照野之設計與評估/ 曾雁明陳臣苑陳汶城林俊彥姚學華李紳豪曾振淦
RARELY REPORTED LIVER TOXICITY IN PATIENTS WHO WERE HEPATITIS B CARRIER AND UNDERWENT CHEMOIRRADIATION FOR GASTRIC CANCER/ Chao-Ming HuangJason Chia-Hsien ChengStella Y. TsaiMei-Ching LiuYih-Lin ChungSkye Hon-Giun ChengWei-Tse FangPo-Sheng YangJames Jer-Min JianAndrew T. Huang
A DOSIMETRIC COMPARISON OF THE PREDICTIVE VALUE OF TWO RECTAL REFERENCE POINTS FOR LATE RECTAL COMPLICATIONS FOLLOWING THE TREATMENT OF CERVICAL CANCER BY HIGH-DOSE-RATE BRACHYTHERAPY/ Shang-Wen ChenJi-An LiangShih-Neng YangHui-Ling KoCheng-Pang TuAn-Cheng ShiauFang-Jen Lin
子宮頸癌術後放射線治療病人組織病理學預後因子之多變數分析/ 賴耿光馬玉麟許瑞昌葉坤土賴義雄林隆堯周明智
胸部固定器設計與臨床上之應用/ 呂宗憲蕭世禎吳錦榕阮昭銘朱慶文葉如?彭秋萍游佩潔
 
   
 
   

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