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題名:使用輻射變色膠片於卡波西氏肉瘤放射線治療的活體劑量驗證     (16點)
IN VIVO SKIN DOSE MEASUREMENT WITH GAFCHROMIC EBT FILM IN THE TREATMENT OF EPIDEMIC KAPOSI'S SARCOMA ON THE FEET WITH RADIATION THERAPY
著者:溫嘉綺(Chia-Chi Wen) ;葉恬綺(Tien-Chi Yeh) ;楊凱鈞(Kai-Chun Yang) ;許仲賢(Chung-Hsien Hsu) ;王雱儀(Pang-I Wang) ;吳任弘(Ren-Hong Wu) ;柯卉玲(Hui-Ling Ko) ;季匡華(Kwan-Hwa Chi)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:輻射變色膠片 ; 卡波西氏肉瘤 ; 組織填充物 ; 活體劑量驗證 ; Gafchromic EBT film ; Kaposi's sarcoma ; Bolus ; In-vivo dosimetry
刊名:放射治療與腫瘤學
頁碼:137-144
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

目的:卡波西氏肉瘤的特性主要為侵犯皮膚組織,臨床上常使用組織補償物增加表面劑量。此次 研究目的為評估個別侵犯單腳與雙腳皮膚的卡波西氏肉瘤病人,因不同適應症而搭配兩種不同組 織補償物,使用 Gafchromic EBT 膠片做為活體劑量計,經由臨床實測,記錄每天劑量變化情形, 藉以作為醫生客觀評估皮膚劑量的依據。 材料與方法:分成兩種不同的治療擺位方式,皆貼上 2×2 cm2 大小的 EBT膠片,用以量測皮膚 劑量。第一種為雙腳皆需要接受放射線治療的病人,雙腳併攏置於水箱中,使用能量 10 MV光子 進行兩側對照,單次處方劑量為 300 cGy,共治療 12 次;第二種為僅需單腳局部接受放射線治療 的病人,使用發泡劑固定系統,添加厚度至少 3 mm 以上的 Polyflex II 當作組織補償物,照射方式 為使用 4 個入射角度的三度空間順形放射治療,光子能量為 4 MV,單次處方劑量為 200 cGy,預 計治療 25 次,治療計畫系統為 Philips pinnacle3 v7.6c。 結果:雙腳照射中,12 個量測點重複量測 5 天,雙腳皮膚平均劑量為 313.3±15.7 cGy;單腳照 射中,2 個量測點重複量測 10 天,A點處的皮膚平均劑量為 219.5±4.1 cGy;B點處的皮膚平均 劑量為 219.0±5.5 cGy,治療計畫計算結果A點為 212.7 cGy,其測量結果比治療計畫多 3.2%; 而B點計算結果為 216.7 cGy,其測量結果比治療計畫多 1.1%。 結論與討論:文中使用的兩種設置方式,不論是使用水或 Polyflex II 當作組織補償物,經過活體劑 量量測,證實都可以使皮膚得到足夠的劑量,甚至接受到約高於處方劑量 10%左右的值,提供給 醫師作為日後客觀評估皮膚劑量的依據。 [ 放射治療與腫瘤學2010; 17(2): 137-144]
Purpose : Epidemic Kaposi's sarcoma mainly invades skin tissues. In the clinic, we often use bolus to increase the surface dose. To evaluate the patients of epidemic Kaposi's sarcoma who had lesions on either single foot or on both feet skins, Gafchromic EBT film was used as in-vivo dosimetry to compare two different radiotherapy methods and verified the skin doses. Materials and Methods : In these two different treatment methods, we used 2×2 cm2 size EBT film to measure the skin dose. The first method treated both feet. Two feet were immersed in a water tank and irradiated with 10 MV bilateral photon beam. The total dose of 36 Gy was delivered in 12 fractions. The second method treated only partial single foot, and used the Alpha cradle fixation system. In this study, we used at least 3mm thick Polyflex II as the tissue-compensator. Base on CT images, the treatment site was irradiated with 4 MV photon beams at 4 different angles. The total dose of 50 Gy was delivered in 25 fractions. The treatment planning system used in this study was Philips pinnacle3 v7.6c. Results : In both-feet irradiation case, we chose twelve points and repeated measurement for 5 days. The average skin dose of both feet was 313.3±15.7 cGy. In single foot irradiation case, two measure points were repeated for 10 days. The average skin dose at points A and B were 219.5±4.1 cGy and 219.0±5.5 cGy respectively. The calculation results of treatment planning at A and B points were 212.7 cGy and 216.7 cGy respectively. The measurement results were higher than the treatment planning system by 3.2% and 1.1%. Conclusions : As shown by the results of this study, either water tank or polyflex II may be used as tissue-compensators. They can provide sufficient doses to the skin tissue. Both methods are available for follow-up evaluation. [Therapeut Radiol Oncol 2010; 17(2): 137-144]


    

本卷期目次
放射治療與腫瘤學
PRELIMINARY RESULTS OF INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF NASOPHARYNGEAL CARCINOMA/ You-Kang ChangJing-Min HwangChiou-Shiung ChangSemon Wu
THE IMPACT OF DYNAMIC PAROTID VOLUME CHANGES AND BODY WEIGHT LOSS ON DOSE DISTRIBUTIONS FOR PATIENTS WITH NASOPHARYNGEAL CANCER RECEIVING INTENSITY-MODULATED RADIATION THERAPY/ Chia-Hsuan LaiMiao-Fen ChenChao-Hsiung HungKuo-Chi LiuWen-Hung WangWen-Cheng Chen
利用影像導引放射治療技術來評估擺位誤差對於計劃靶體積包覆率的影響/ 劉義誠劉煥彰陳柏元陳臣苑張安進程言鼎曾雁明洪志宏
使用輻射變色膠片於卡波西氏肉瘤放射線治療的活體劑量驗證/ 溫嘉綺葉恬綺楊凱鈞許仲賢王雱儀吳任弘柯卉玲季匡華
SMALL CELL CARCINOMA OF EXTERNAL AUDITORY CANAL: A CASE REPORT/ Chia-Wei ShenYu-Chang HuWei-Ming LaiChien-Hsun ChenChung-Man LeungKuo-Chen ChangChing-Hsiung Chang
PULMONARY KAPOSI'S SARCOMA IN A PATIENT WITH HIV INFECTION: A CASE REPORT/ Tzu-Hwei WangYung-Hsiang HsuWen-Lin Hsu
ONCOCYTIC CARCINOMA OF THE SUBMANDIBULAR GLAND, FROM BENIGN TO MALIGNANT--A REPORT ON AN UNUSUAL CASE/ Jenny QueLi-Ching LinWen-Ying LeeKue-Li LinChia-Hui LinYu-Wei LinChing-Chieh Yang
LONG-TERM OUTCOMES OF RADIOTHERAPY FOR PRIMARY PEDIATRIC BRAIN TUMORS: STATISTICS AND STRATEGIES OF A SINGLE INSTITUTE IN TAIWAN/ Kai-Lin YangPin-I HuangTai-Tong WongKai-Ping ChangLing-Wei WangCheng-Ying ShiauYu-Ming LiuKeng-Li LanYu-Wen HuI-Chun LaiYi-Wei ChenSang Hue Yen
 
   
 
   

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