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題名:RETROSPECTlVE ANALYSIS OF OUTCOMES FOR PATIENTS WITH INVASIVE THYMOMA RECEIVING SURGERY WITH OR WITHOUT ADJUVANT RADIOTHERAPY     (20點)
胸腺瘤術後之預後與有無輔助性放射治療之回朔性研究
著者:Wan-yu Chen(陳婉瑜) ;Jason Chia-Hsien Cheng(成佳憲) ;Yung-Chie Lee(李元麒) ;Feng-Ming Hsu(許峯銘)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:胸腺瘤 ; 手術 ; 輔助性放射治療 ; 預後因子 ; Invasive thymoma ; Surgery ; Adjuvant radiotherapy ; Prognostic factor
刊名:Therapeutic Radiology and Oncology
頁碼:17-26
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

且且:針對侵襲性胸腺瘤術後患者,探討相關之預後因子與術後輔助性放射線治療的模式。 材料及育法:本研究包含63 位侵襲性胸腺瘤患者。所有病患均接受手術,其中49 位病患接受 術後輔助性放療。回顧分析病人相關特徵如年齡、性別、胸腺瘤期別、有無重症肌無力以及治 療相關因子如手術切除程度、放射線劑量與照野。 益星:五年之存活率以及無病之存活率分別為83% 及8 1.5% 。最常見之復發位置為肋膜復發。 單變項分析發現Mosaoka 期別與手術切除程度為重要之預後因子。第H 期與第IWIV 期病人之 5 年存活率分別為95.8% 與7 1. 9% (p= 0.06 )。手術達到完全切除相較於顯微鏡下或巨觀殘存腫 瘤的患者的5 年存活率分別為87.3% 與44 .4% (p= 0 . 04 ) 。接受大範圍縱隔腔或縱隔腔及鎖骨 上淋巴照射的病人,與接受小範圍腫瘤切除周圍照射的病人在5 年的存活率沒有統計上顯著差 異,分別為88% 與94.7% (p= 0.53) 。在無病存活率方面,本研究並未找到重要的預後因子。 誼益:本研究發現手術切除程度為侵襲性胸腺瘤最重要之預後園子。預防性照射縱隔腔對治療 結果並無顯著進步。
PU盟旦旦: To investigate the prognostic factors associated with outcome in patients with invasive thymoma undergoing surgery with or without adjuvant radiotherapy and strategies for optimal adjuvant radiotherapy. M'ethods and Materia/.~ : This retrospective study included 63 patients with invasive thymoma. AII patients received surgery and 49 patients ' underwent adjuvant radiotherapy. Patient characteristics and treatment related parameters were analyzed to correlate with overall survival and disease free survival 且重皇ults : The 5-year overall survival and disease-free survival rate was 83% and 81.5% , respectively. The most common site of failure is pleural seeding. The univariate analyses showed that Mosaoka stage and extent of surgical resection were important prognostic factors. The 5-year overall survival rate was 95.8 % in stage 11 thymoma and 71 .9% in stage III/IV thymoma (p= 0.06). The 5-year survival rate was 87.3% for those who underwent complete resection compared with 44.4% for those with microscopic or gross residual disease (p= 0.04). Patients receiving extendedfield or involved-field radiotherapy had similar 5-year overall survival (88% versus 94.7%, p= 0.53). In this study, we can not identify significant prognostic factors for disease free survival. 主金且皇位畫但!1 : In our study, the extent of resection is important prognostic factor for invasive thymoma. Extensive radiation field covering mediastinum is not associated with better outcome.


    

本卷期目次
Therapeutic Radiology and Oncology
電腦刀呼吸同步追蹤系統應用於放射治療之評估/ 郭駿騵林家瑋蕭安成余孝緯陳尚文鍾道生陳秋萍林招膨蔡若婷
RETROSPECTlVE ANALYSIS OF OUTCOMES FOR PATIENTS WITH INVASIVE THYMOMA RECEIVING SURGERY WITH OR WITHOUT ADJUVANT RADIOTHERAPY/ Wan-yu ChenJason Chia-Hsien ChengYung-Chie LeeFeng-Ming Hsu
THE CLINICAL OUTCOME OF NEOADJUVANT CHEMORADIOTHERAPY IN LOCALLY ADVANCED RECTAL CANCER/ Chien-Chih ChenHui-Ling YehJin-Ching LinWei-Ming WangY.C. Jeffrey ChaoChen-Fa ChangJia-Fu Lin
COMPARISON OF TREATMENT RESULTS OF MALIGNANT ASTROCYTOMA AFTER POST-OP RADIOTHERAPY ALONE OR POST-OP CONCURRENT CHEMORADIOTHERAPY PLUS ADJUVANT EMOTHERAPY--EXPERIENCE IN TSGH/ Kuen-Tze LinChing-Jung WuYee-Min JenMeei-Shyuan, LeeWen-Yen HuangChang-Ming ChenHsing-Lung ChaoChun-Shu LinYu-Fu SuJang-Chun Lin
EVALUATION OF PROSTATE CANCER TREATED WITH TEMPORARY IDGH DOSE RATE INTERSTITIAL BRACHYTHERAPY AND FOLLOWED BY EBRT/ Li-Chu PaiShi-Long LianChih-Jen HuangChia-Chu LiuWen-Jeng WuHuan-Chun HsiehShu-Pin Huang
利用射束阻擋法修正三維正子造影之非真實事件貢獻/ 郭瓊蓮林信宏莊克士詹美玲羅素花王裕文
MAILGNANT LYMPHOMA INVOLVING THE PROSTATE: A CASE REPORT/ Li-Min SunEng-Yen HuangNai-Jen ChangLi-Min ChungChiao-Yi LuJi-An LiangMan-Gang Lee
PROSTATE CANCER OF A YOUNG MAN: A CASE REPORT AND REVIEW OF LITERATURE/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangLi-Chung HungYung-Hsien Liu
BASAL CELLADENOCARCINOMA OF PAROTID GLAND: A CASE REPORT IN TAIWAN/ Ting-An ChangJyh-Der LeuChien-Ru Liu
 
   
 
   

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