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題名:利用射束阻擋法修正三維正子造影之非真實事件貢獻     (18點)
CORRECTION OF NON-TRUE COINCIDENCE IN 3D PET USING BEAM STOPPER DEVICE
著者:郭瓊蓮(Cyong-Lian Guo) ;林信宏(Hsin-Hon Lin) ;莊克士(KS Chuang) ;詹美玲(Meei-Ling Jan) ;羅素花(Su-Hua Lo) ;王裕文(Yu-Wen Wang)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:射束阻擋 ; 散射事件 ; 隨機事件 ; Beam stopper ; Scatter event ; Random event
刊名:放射治療與腫瘤學
頁碼:59-67
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

且且:正子斷層造影掃描是在核子醫學上一項非侵襲性的檢查技f椅,提供臨床上功能性生理資 訊。目前常用三維擷取模式來提高造影的靈敏度,但隨機與散射同符事件因此提高。一般隨機事 件修正是利用即時的延遲時間窗修正法;散射事件修正是利用單;欠散射光子模擬法,然而以上修 正法皆有缺失影響修正後的準確性。為有效矯正正子造影非真實事件,故提出利用蒙地卡羅模擬 旋繞式射東阻擋裝置修正法。 姐姐盟主法本研究使用GATE 蒙地卡羅軟體模擬microPET R4 系統以及射東阻擋修正法。利 用射東阻擋裝置在不同角度下兩組正弦圖受檔塊遮蔽下的資訊J 交叉計算出其非真實事件的貢獻 量,因非真實事件分布是緩慢變化函數,所以可根據擋塊遮蔽部份的取樣點利用cubic-spline 內 搞法得到整張正弦圈中非真實事件分布情形,再進行矯正。 鐘星星:本實驗研究優點在提出能窗飽團較大靈敏度提升的同時,掃描時間保持固定,射東修正法 矯正的非真實事件分率31 . 55% 與蒙地卡羅非真實事件分率29 . 62% 的結果最相近,而且矯正後假 體區域活度分佈也較接近實際活度比例的分配。 鐘畫畫:艇繞式射東阻擋法在不額外增加造影掃描時間的情況下,利用射東阻擋裝置轉換位置來提 高實驗取樣結果,矯正效果接近蒙地卡羅結果。相信本研究所提出的矯正法是更適合於正子斷層 造影鶴床上應用。 [放射治療與腫瘤學2011; 18(1): 59-67]
主坐血型g : Position Emission Tomography (PET) is a non-invasive technique used in nuc1ear medicine, which provides physiological information using molecular tracers. As 3D PET data acquisition increases, random and scatter coincidence events increase relevantly. They cause a uniform distribution of background on the image and degrade the accuracy of quantitative analysis. The conventional corrections for random and scatter coincidences are achieved by the delayed window technique and Single Scatter Simulation (SSS) method. However, they increase noise and reduce lmage accuracy. M'aterial and Method~. : The aim of this study is to examine the feasibility of using a beam stopper (BS) for correcting non-true coincidence events. The BS placed on the line of response (LOR) at two different locations rotating with constant degrees absorbs a particular fraction of the true events. The non-true coincidence, non-blocked at the LORs by each s切pper, can be estimated. Assuming that thβnon-true radiation is a spatially slow-varying distribution, the whole non-true sinogram can be recovered using cubic-spline interpolation from these local measurements. Beam stopper rotated (BSR) reduces the effective sampling distance without increasing the number of the stoppers. In this study, we performβd Monte Carlo (MC) simulations for 3-D PET with the GATE software for a cold phantom to conduct the BSR method. 主監益11 : The estimate of non-true event fraction in a large FOV using BSR method is 31.55% and is c10se to the result of Monte-Carlo simulation. The activity ratio of region approaches the initial input quant1ty. C'onclusio!! : We conc1ude that the proposed correction method is effective and better than conventional correction schemes without increasing scan time. In sum, the BSR method is a convenient and effective correction for non-true coincidences in 3D PET. [Therapeut Radiol Onco12011; 18(1): 59-67]


    

本卷期目次
放射治療與腫瘤學
電腦刀呼吸同步追蹤系統應用於放射治療之評估/ 郭駿騵林家瑋蕭安成余孝緯陳尚文鍾道生陳秋萍林招膨蔡若婷
RETROSPECTlVE ANALYSIS OF OUTCOMES FOR PATIENTS WITH INVASIVE THYMOMA RECEIVING SURGERY WITH OR WITHOUT ADJUVANT RADIOTHERAPY/ Wan-yu ChenJason Chia-Hsien ChengYung-Chie LeeFeng-Ming Hsu
THE CLINICAL OUTCOME OF NEOADJUVANT CHEMORADIOTHERAPY IN LOCALLY ADVANCED RECTAL CANCER/ Chien-Chih ChenHui-Ling YehJin-Ching LinWei-Ming WangY.C. Jeffrey ChaoChen-Fa ChangJia-Fu Lin
COMPARISON OF TREATMENT RESULTS OF MALIGNANT ASTROCYTOMA AFTER POST-OP RADIOTHERAPY ALONE OR POST-OP CONCURRENT CHEMORADIOTHERAPY PLUS ADJUVANT EMOTHERAPY--EXPERIENCE IN TSGH/ Kuen-Tze LinChing-Jung WuYee-Min JenMeei-Shyuan, LeeWen-Yen HuangChang-Ming ChenHsing-Lung ChaoChun-Shu LinYu-Fu SuJang-Chun Lin
EVALUATION OF PROSTATE CANCER TREATED WITH TEMPORARY IDGH DOSE RATE INTERSTITIAL BRACHYTHERAPY AND FOLLOWED BY EBRT/ Li-Chu PaiShi-Long LianChih-Jen HuangChia-Chu LiuWen-Jeng WuHuan-Chun HsiehShu-Pin Huang
利用射束阻擋法修正三維正子造影之非真實事件貢獻/ 郭瓊蓮林信宏莊克士詹美玲羅素花王裕文
MAILGNANT LYMPHOMA INVOLVING THE PROSTATE: A CASE REPORT/ Li-Min SunEng-Yen HuangNai-Jen ChangLi-Min ChungChiao-Yi LuJi-An LiangMan-Gang Lee
PROSTATE CANCER OF A YOUNG MAN: A CASE REPORT AND REVIEW OF LITERATURE/ Chia-Chun HuangMu-Tai LiuChu-Ping PiTung-Hao ChangLi-Chung HungYung-Hsien Liu
BASAL CELLADENOCARCINOMA OF PAROTID GLAND: A CASE REPORT IN TAIWAN/ Ting-An ChangJyh-Der LeuChien-Ru Liu
 
   
 
   

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