原名「台灣學術線上」
包含TAO期刊庫 + TAO書籍庫 + 論文 + 史料文獻
首頁 | 關於TAO | 瀏覽 | 進階查詢 | 參考工具 | 會員服務 | 已購專書 | RSS服務 | 電子報 | FAQ  
查詢範圍:
   
查詢模式:
熱門查詢詞:
老人需求dvdTaiwan vet雞濾泡顆粒細胞
   
   
   
     
   
 
項次 書目
1
題名:TREATMENT OUTCOME OF NEOADJUVANT CHEMORADIOTHERAPY FOR ESOPHAGEAL SQUAMOUS CELL CARCINOMA IN OUR INSTITUTION     (16點)
食道鱗狀上皮癌術前合併放射與化學治療的治療結果
著者:Kuo-Chen Chang(張國楨) ;Wen-Shan Liu(劉文山) ;Ching-Hsiung Chang(張慶雄) ;Yu-Chang Hu(胡渝昌) ;Chien-Hsun Chen(陳建勳) ;Chung-Man Leung(梁頌文)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:食道癌 ; 術前同步放射與化療治療 ; 腫瘤減少程度 ; Esophageal cancer ; Neoadjuvant chemoradiotherapy ; Tumor regression grade
刊名:Therapeutic Radiology and Oncology
頁碼:171-178
語言:英語
摘要: 中文摘要PDF ; 英文摘要PDF

目的:在此回顧性研究中,我們評估食道癌接受術前同步放射與化療的治療結果,以及術後病理腫瘤減少程度與淋巴節是否有侵犯對總體存活的影響。
材料與方法:
以回溯性的方法,從1999年6月至2011年4月,64位食道癌的病人接受術前同步放射與化療的治療,對術後病理腫瘤減少程度、淋巴節是否有侵犯、病理分期、復發的模式與整體存活加以記錄和分析,以Kaplan-Meier方法計算無病和總體存活率,用log-rank test去作組別間的比較。Cox迴歸分析來檢查多變數的影響。
結果:中位存活為24.2個月(範圍從3-92個月),比較術後病理腫瘤減少程度1 (TRG1)與TRG2-4總體存活率(OS)沒有差異(P=0.549),當TRG1-2與TRG3-4比較總體存活率(OS)有差異的趨勢(P=0.089)。術後病理顯示沒有淋巴節侵犯與有淋巴節侵犯的中位存活分別為23.6及13.5個月(P<0.001)。在單變數分析中淋巴節侵犯(P<0.001)與血管侵犯(P=0.041)會影響總體存活率。有淋巴節侵犯較易遠端轉移(P=0.001),TRG3-4則較易局部復發(P=0.008)。在多變數分析中只有淋巴節侵犯有意義的影響總體存活率(P=0.004),血管侵犯(P=0.658)則沒有相關。
結論:對於接受術前同步放射與化療治療的病人,術後病理顯示沒有殘存的淋巴節侵犯是重要的預後因子。術後病理腫瘤減少程度較不能作為預後的因子。
Purpose: In this retrospective study, we evaluated the treatment outcome following neoadjuvant chemoradiotherapy for esophageal cancer and the impact of tumor regression and post operative nodal status.
Materials and Methods: Sixty-four patients of esophageal cancer treated with neoadjuvant chemoradiotherapy from June, 1999 to April, 2011 were followed retrospectively. Tumor regression grade (TRG), post operative nodal status, pathologic stage, pattern of recurrence and overall survival (OS) of these patients were recorded and analyzed. Disease-free and overall survival rates were calculated with Kaplan-Meier method and group comparisons were based on the log-rank test. Cox regression analysis was the method applied when several factors were assessed simultaneously.
Results: Median survival is 24.2 months (range, 3-92 months). Comparing TRG 1 with TRG 2-4, the OS was not significantly different (P=0.549). When TRG1-2 was compared with TRG3-4, there was a trend of significant difference in OS (P=0.089). The median survival was 23.6 months in the N-group, compared with 13.5 months in the N+ group (P<0.001). In univariate survival analysis, N+(P<0.001) and vascular involvement (P=0.041) significantly influence survival probabilities. N+ was significantly (P=0.001) associated with distant metastasis and TRG 3-4 (P=0.008) with locoregional recurrence. By multivariate analysis, only N+ significantly influence OS (P=0.004) and vascular involvement (P=0.658) was not significant.
Conclusion: For those who are receiving neoadjuvant chemoradiotherapy, achieving node-negative status is a significant prognostic factor for the outcome. As for histomorphologic tumor regression, it has a less predictive factor.


    

本卷期目次
Therapeutic Radiology and Oncology
CLINICAL-PATHOLOGIC FEATURES AND OUTCOMES OF RADIATION THERAPY IN A LARGE COHORT OF PATIENTS WITH OP ERABLE BREAST CANCER/ Yu-Hsuan LaiHung-Yu ChenKai-Hsiang ChanHelen H.W. Chen
TREATMENT OUTCOME OF NEOADJUVANT CHEMORADIOTHERAPY FOR ESOPHAGEAL SQUAMOUS CELL CARCINOMA IN OUR INSTITUTION/ Kuo-Chen ChangWen-Shan LiuChing-Hsiung ChangYu-Chang HuChien-Hsun ChenChung-Man Leung
GAMMA KNIFE PERFEXION® RADIOSURGERY FOR INTRAOCULAR TUMOR-TECHNIQUE ESTABLISHMENT AND PRELIMINARY RESULTS/ Yi-Chieh TsaiJia-Wei LinShih-Chung LaiAn-Cheng ShiauChih-Chieh ChangJo-Ting Tsai
應用類神經網路預測鼻咽癌病人之五年存活狀態/ 鄭中浩鄭鴻鈞邱泓文
COMPARISON OF THE REFERENCE DOSIMETRY ACCORDING TG-21 PROTOCOL AMONG SOLID PHANTOMS/ Hui-Ju TienAn-Cheng ShiauHsin-Pei YehChi-Ta LinHo-Hsing ChenHsiu-Wen LeeChao-Hsiung HungChung-Hsien HsuPei-Wei Shueng
銥-192近接治療射源之劑量計算與測量研究/ 何秀雯張寶樹林立青
PRIMARY OSTEOSARCOMA OF THE BREAST: A CASE REPORT IN TAIWAN/ Wen-Hsin HungJung-Mao ChouChien-Ru LiuJyh-Der Leu
HIGH DOSE RADIOTHERAPY OF AN ESOPHAGEAL CANCER PATIENT WITH CARDIAC PACEMAKER IMPLANTATION-A CASE REPORT/ Yo-Liang LaiJi-An LiangKuo-Hung LinChun-Ru Chein
 
   
 
   

與TAO合作 | 隱私與版權聲明 | 聯絡方式 | 下載Adobe Reader
地址:台北市中正區(100)北平東路30-12號3樓
電話:(02)2393-6968 傳真:(02)2393-6877
Email: service@wordpedia.com
Wordpedia Family: 學校、企業版入口 | 遠流影音館
Copyright©2011 Wordpedia Co., Ltd. All Rights Reserved.