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題名:電腦斷層治療機照野寬度與螺距參數設定對治療計畫的影響:假體實驗     (20點)
The Influence of Fi eld Width and Pit ch in Tomotherapy Plan: Phantom study
著者:吳任弘(Ren-Hong Wu) ;葉恬綺(Tien-Chi Yeh) ;溫嘉綺(Chia-Chi Wen) ;王雱儀(Pang-I Wang) ;蕭仟翊(Chien-Yi Hsiao) ;許仲賢(Chung-Hsien Hsu)
出版地區:台灣
出版城市:台北市
學科:醫學綜合
關鍵字:電腦斷層治療 ; 螺距 ; 漣波效應 ; 放射治療計畫 ; Tomotherapy ; Pitch ; Ripple effect ; Radiotherapy plan
刊名:放射治療與腫瘤學
頁碼:131-140
語言:繁體中文
摘要: 中文摘要PDF ; 英文摘要PDF

目的:電腦斷層治療機(Tomotherapy®)以旋進(helical)方式傳遞劑量,因此照野寬度(field width)與螺距(pitch)兩個參數的設定,會對治療計畫的結果產生一定之影響。本實驗目的在比較不同的照野寬度與螺距設定,在均勻假體中對治療計畫結果的影響。
材料與方法:以電腦斷層掃描儀取得圓柱型固態水假體(Med Cal, Verona, WI)之斷層影像。繪製靶體積與危急器官輪廓、執行相同的最佳化疊代次數與相同的靶體積與危急器官權重,僅設定不同照野寬度(5cm、2.5cm、1cm)及螺距參數(0.2、0.4、0.6、0.8)。比較整體時間、靶體積之均勻指標與頭腳向之漣波效應(ripple effect)以及危急器官接受的劑量。
結果:結果顯示當機頭旋轉一圈所花週期大於最快週期時,照射時間與螺距值無關而與照野寬度有關,5cm、2.5cm、1cm所需的照射時間比值約為1:1.8:4。當螺距太小,使得機頭旋轉週期小於15秒時,為配合機器最快週期的限制,旋轉週期會延長為機頭的最快週期,使照射時間增長。照野寬度愈大頭腳向劑量半影區愈大。螺距設定0.6時靶體積內有明顯的漣波效應,此時靶體積的均勻度最差。靶體積順形度在橫切面上並無明顯差異,照野寬度愈小在照野邊緣頭腳向的劑量梯度愈大。小照野寬度與小螺距對危急器官的保護最佳。另均勻假體內,落在AP方向的危急器官接受的平均劑量比側向高。
討論:由結果可得照射時間與照野寬度有明顯相關,若以治療時間為主,可考慮用大照野寬度搭配小螺距,但位於靶體積外側頭腳向區域的劑量會增加。若以計畫品質為主,則使用小照野寬度與小螺距,但治療時間會增加。
Purpose : Field width (FW) and pitch factor (PF) are parameters that influence the quality of treatment plans and beam-on times in Tomotherapy that delivers helical radiation therapy. This study examines the relationship between these parameters and their influence on the quality of treatment plan.
Material and Method : Target volumes and organ at risk (OAR) volumes were delineated on a computerized tomography of a cylindrical chess phantom. Maintaining the weightings of each volume, treatment plans were optimized with a different combination of planning parameters (FW = 5, 2,5, 1 cm. PF = 0.2, 0.4, 0.6, 0.8). Each plan was analyzed for dose distribution, treatment time, homogeneity index, conformity index and ripple effect.
Result : For revolutions lasting between 15 and 60 seconds, the increase in treatment time correlated with decreasing field width. The ratio between treatment time with different field widths, when treatment time at 5 cm was 1, 1.8 and 4 times at widths of 2.5 cm and 1 cm respectively. Where change in pitch factor was did not result in change in treatment time. For revolutions under 15 seconds, smaller pitch denotes longer treatment time. The dimension of penumbra increased with increasing width. At pitch factor 0.6, the ripple effect was evident and the homogeneity index was at its worst. Transversely, conformity indices differed non-significantly. Longitudinally, the dose gradient increased with decreasing field width. Doses to OARs were minimized at small pitch and field width. OARs in longitudinal direction had higher median dose.
Conclusion : Change in field width could lead to change in treatment time. Treatment time could be shortened with combination of large field width and the pitch value, at expense of increased dose to longitudinal directions. Combination of small field width and small pitch yielded better planning quality, and increase in treatment time.


    

本卷期目次
放射治療與腫瘤學
Image-Guided Stereotactic Radiosurgery Usi ng Volumetric Modulated Arc Therapy for Arteriovenous Malformation of the Brain: Experiences of a Single Institution/ Chia-Chun HuangTung-Hao ChangChu-Ping PiLi-Chung HungTsai-Wei Chou
Radiotherapy for Intracranial Germinoma: Tr eatment Modalities and Clinical Outcome/ Yu-Jen WangFeng-Ming HsuYu-Hsuan ChenChiao-Ling TsaiWan-Yu ChenJason Chia-Hsien ChengSung-Hsin Kuo
惡性間皮細胞瘤應用銳速刀與強度調控放射治療計劃之比較/ 賴鵬安劉芳慧賴耿光葉啟源
電腦斷層治療機照野寬度與螺距參數設定對治療計畫的影響:假體實驗/ 吳任弘葉恬綺溫嘉綺王雱儀蕭仟翊許仲賢
ADJUVANT RADIOTHERAPY FOR RECURRENT MUCOEPIDERMOID CARCINOMA OF THE ORBIT: A CASE REPORT AND REVIEW OF LITERATURE/ Nan-Tsung WangChing-Jung WuShih-Hung Huang
PRIMARY SMALL CELL CARCINOMA OF THE URETER - A CASE REPORT AND REVIEW OF THE LITERATURE/ Yu-An ChienTung-Hao ChangMu-Tai LiuChu-Ping PiChia-Chun HuangLi-Chung HungTsai-Wei Chou
Hemoglobin Level during Chemoradiation Th erapy Predicts Treatment Outcome in Nasopharyngeal Cancer/ Bing-Jie ShenPei-Wei Shueng
A RETROSPECTIVE COMPARISON OF TREATMENT RESULTS AMONG GBM PATIENTS TREATED WITH DIFFERENT RADIOTHERAPY PROTOCOLS/ Shang-Yu ChouChun-Chieh HuangYu-Jie HuangFu-Min FangEng-Yen HuangChong-Jong WangHui-Chun ChenYu-Ming WangHsuan-Chih Hsu
 
   
 
   

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